PMID: 9183496May 1, 1997Paper

The influence of dietary nucleotides on erythrocyte membrane fatty acids and plasma lipids in preterm infants

Acta Paediatrica
I AxelssonA Warm

Abstract

The objective of this study was to evaluate whether a regular formula for premature infants supplemented with nucleotides has any influence on plasma lipids and erythrocyte membrane fatty acids. Preterm infants fed either human milk supplemented with human milk protein (HM, n = 14), nucleotide-supplemented preterm formula (NF, n = 13), or a regular preterm formula (F, n = 13) were included in the study. The NF was supplemented with 18.2 mg cytidine monophosphate/l (CMP), 7.0 mg uridine monophosphate/l (UMP), 6.4 mg adenosine monophosphate/l (AMP), 3.0 mg inosine monophosphate/l (IMP) and 3.0 mg guanosine monophosphate/l (GMP). There were significantly higher concentrations of triglycerides (TG) in infants fed NF compared to those fed F (191.42 +/- 79.58 vs 108.21 +/- 43.73, p < 0.001, mean +/- SD lipid concentrations, mg/100 ml plasma). Infants fed F had significantly lower concentrations of total cholesterol (94.34 +/- 11.71 vs 115.69 +/- 39.29, p < 0.01) and TG in plasma (108.21 +/- 43.73 vs 172.27 +/- 68.19, p < 0.001, mean +/- SD lipid concentrations, mg/100 ml plasma) when compared to HM-fed infants. There were no significant differences in any of the erythrocyte membrane fatty acids and total long-chain polyunsaturated fa...Continue Reading

References

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Citations

Dec 17, 2003·Journal of Pediatric Gastroenterology and Nutrition·Tania SiahanidouDimitris Anagnostakis
Jun 28, 2006·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Fabio ScopesiGiovanni Serra
Mar 14, 2008·Journal of Animal Physiology and Animal Nutrition·L-F WangY-H Shi
Nov 24, 1999·Current Opinion in Clinical Nutrition and Metabolic Care·F B Rudolph, C T Van Buren
Feb 24, 2021·The Cochrane Database of Systematic Reviews·Laura PerrettaHeather L Brumberg
Jun 3, 2021·Animals : an Open Access Journal From MDPI·Federico CorreaPaolo Trevisi

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