The influence of drugs and disease activity on biochemical and haematological data in rheumatoid arthritis.

Clinica Chimica Acta; International Journal of Clinical Chemistry
P WildingM Farr

Abstract

Biochemical and haematological data from 218 patients with rheumatoid arthritis were analysed and compared with data from a reference hospital population. The comparison demonstrated significant differences in several biochemical and haematological tests and that the patterns of change are different between males and females. The data were also analysed by conventional statistical methods and discriminant analysis using a computer to establish which tests were most influenced by the activity of the disease and drug therapy. The results obtained demonstrate marked difference between groups of patients with different disease activity or receiving different drugs. The discriminant analysis also identified those tests which differentiate these groups most effectively.

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Citations

May 29, 2000·Pathophysiology : the Official Journal of the International Society for Pathophysiology·J Ahlqvist
Feb 24, 1977·The New England Journal of Medicine·R P Kimberly, P H Plotz
Feb 1, 1990·Journal of Clinical Pharmacy and Therapeutics·M J KendallR Rau
Oct 1, 1983·Annals of the Rheumatic Diseases·M FarrJ Stuart
Jun 1, 1991·Annals of the Rheumatic Diseases·S Rantapää-DahlqvistG Dahlén
Jan 1, 1980·Scandinavian Journal of Rheumatology·J ViikariT Terho

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