The Influence of Fat Grafting on Skin Quality in Cosmetic Foot Grafting: A Randomized, Cross-Over Clinical Trial

Aesthetic Surgery Journal
Stephanie E FarberJeffrey A Gusenoff

Abstract

Pedal fat grafting is a cosmetic procedure to treat the functional and aesthetic sequelae of pedal fat pad atrophy. Fat grafting has been found to mitigate these symptoms, but the exact mechanism is unknown. The authors hypothesized that pedal fat grafting may improve skin quality, accounting for prolonged symptomatic improvement despite loss of grafted fat. Patients with pedal atrophy were enrolled in a randomized crossover clinical trial. Group 1 underwent fat grafting upon enrollment with 2-year follow-up. Group 2 was managed conservatively for 1 year then placed into the fat grafting group with 1-year follow-up. Patients underwent pedal ultrasounds to determine thicknesses of the fat pad and dermis, and photographs were taken to assess skin quality. Three men and 20 women with an average age of 63 ± 6 years and an average BMI of 26.0 ± 4.6 kg/m2 were enrolled in the study. Twenty-six feet were injected in Group 1 and 17 were injected in Group 2. Group 1 dermal thickness increased at 6 months post-injection (P < 0.05). This increase persisted through 24 months. Group 2 dermal thickness decreased prior to injection (P < 0.05) but returned to baseline after injection and through 12-month follow-up (P < 0.05). Fat pad thickness...Continue Reading

Associated Clinical Trials

May 7, 2020·Jeffrey A. Gusenoff, MD

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Citations

Mar 16, 2019·Aesthetic Surgery Journal·Achilleas ThomaJenny Santos
Apr 2, 2021·Aesthetic Surgery Journal. Open Forum·Marissa E BaronJeffrey A Gusenoff
Feb 20, 2021·The Journal of Craniofacial Surgery·Haitao XiaoXuewen Xu

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