PMID: 7537879Jan 1, 1995Paper

The influence of gravidity on Down's syndrome screening with free beta hCG

Prenatal Diagnosis
K Spencer

Abstract

Total human chorionic gonadotropin (hCG) levels have been shown in one previous small study to vary with gravidity. In order to establish if maternal serum free beta hCG was similarly affected, approximately 4500 pregnancies of varying gravidity were analysed. The results indicated that there was a 6 per cent higher median MOM in primigravid compared with multigravid women. The impact of such elevation in Down's syndrome screening programmes will be minimal.

References

Oct 11, 1990·American Journal of Obstetrics and Gynecology·J N MacriJ W Larsen
Oct 8, 1988·BMJ : British Medical Journal·N J WaldJ A Canick
Jun 12, 1993·BMJ : British Medical Journal·K SpencerA M Ward
Feb 19, 1994·Lancet·D G DanielM D Penney

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Citations

Mar 17, 2000·Prenatal Diagnosis·I M de GraafJ M van Lith
Dec 1, 1995·Obstetrics and Gynecology·R A MooneyC J Peterson
Jun 10, 1998·Obstetrical & Gynecological Survey·A Conde-Agudelo, A C Kafury-Goeta
Nov 28, 2012·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Tamara IllescasJoaquín Montalvo
Dec 1, 1996·Prenatal Diagnosis·G BarkaiH Cuckle
Jun 15, 2012·The Cochrane Database of Systematic Reviews·S Kate AlldredZarko Alfirevic
Mar 16, 2017·The Cochrane Database of Systematic Reviews·S Kate AlldredZarko Alfirevic
Dec 15, 2015·The Cochrane Database of Systematic Reviews·S Kate AlldredZarko Alfirevic
Dec 1, 2015·The Cochrane Database of Systematic Reviews·S Kate AlldredZarko Alfirevic
Apr 1, 1996·Prenatal Diagnosis·G BarkaiH Cuckle
Jan 1, 1995·Journal of Medical Screening·J E HaddowG J Knight
Mar 16, 2017·The Cochrane Database of Systematic Reviews·S Kate AlldredZarko Alfirevic
Jan 1, 1997·Journal of Medical Screening·N J WaldA McGuire
Nov 19, 2004·Acta Obstetricia Et Gynecologica Scandinavica·Ulrikke LeiMads Melbye

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