The Influence of High-Impact Exercise on Cortical and Trabecular Bone Mineral Content and 3D Distribution Across the Proximal Femur in Older Men: A Randomized Controlled Unilateral Intervention

Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
Sarah J AllisonKatherine Brooke-Wavell

Abstract

Regular exercisers have lower fracture risk, despite modest effects of exercise on bone mineral content (BMC). Exercise may produce localized cortical and trabecular bone changes that affect bone strength independently of BMC. We previously demonstrated that brief, daily unilateral hopping exercises increased femoral neck BMC in the exercise leg versus the control leg of older men. This study evaluated the effects of these exercises on cortical and trabecular bone and its 3D distribution across the proximal femur, using clinical CT. Fifty healthy men had pelvic CT scans before and after the exercise intervention. We used hip QCT analysis to quantify BMC in traditional regions of interest and estimate biomechanical variables. Cortical bone mapping localized cortical mass surface density and endocortical trabecular density changes across each proximal femur, which involved registration to a canonical proximal femur model. Following statistical parametric mapping, we visualized and quantified statistically significant changes of variables over time in both legs, and significant differences between legs. Thirty-four men aged mean (SD) 70 (4) years exercised for 12-months, attending 92% of prescribed sessions. In traditional regions...Continue Reading

References

Jul 1, 1985·Calcified Tissue International·C T Rubin, L E Lanyon
Jan 1, 1995·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·J C LotzW C Hayes
Sep 17, 1998·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·T L JärvinenM Järvinen
Jan 20, 1999·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·K L BellJ Reeve
Jan 20, 1999·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·S AdamiM Rossini
Sep 1, 1999·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·T L JärvinenH Sievänen
Jul 14, 2001·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·N CrabtreeJ Reeve
Aug 7, 2002·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Alexander G RoblingCharles H Turner
Oct 17, 2002·JAMA : the Journal of the American Medical Association·Steven R CummingsDennis M Black
Nov 13, 2003·The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology·Harold M Frost
Apr 2, 2004·Australian Family Physician·Maria A Singh
Oct 30, 2004·Medicine and Science in Sports and Exercise·Wendy M KohrtUNKNOWN American College of Sports Medicine
Apr 13, 2005·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Stuart J WardenJiliang Li
Nov 13, 2008·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·R NikanderH Sievänen
May 8, 2009·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·C David L ThomasJonathan Reeve
Jun 9, 2009·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·C J HamiltonS A Jamal
Jul 15, 2009·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Kenneth E S PooleJonathan Reeve
Oct 13, 2010·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Valérie Danielle BoussonJean-Denis Laredo
Nov 1, 2009·Orthopaedic Surgery·Qi ZhangYing-ze Zhang
Apr 3, 2012·Medical Image Analysis·G M TreeceA H Gee
Oct 31, 2012·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Julio Carballido-GamioThomas F Lang
Apr 24, 2013·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Fjola JohannesdottirGunnar Sigurdsson
Jul 16, 2013·Clinical Biomechanics·Aaron H StrumingerJ Troy Blackburn
Oct 31, 2013·Dento Maxillo Facial Radiology·R C HoogeveenW E R Berkhout
Dec 3, 2013·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Thomas F LangPeter R Cavanagh
Apr 22, 2014·Journal of Biomechanics·Saulo MartelliMarcus G Pandy
Aug 5, 2014·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Kenneth Es PooleCesar Libanati

❮ Previous
Next ❯

Citations

Nov 19, 2015·Biomechanics and Modeling in Mechanobiology·Diogo M GeraldesAndrew T M Phillips
Jul 16, 2015·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Kenneth Es PooleCesar Libanati
Nov 12, 2015·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·B A J SimmondsJ H Tobias
Oct 21, 2017·Biogerontology·Lívia SantosCraig Sale
May 8, 2018·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Philippe WagnerPawel Szulc
May 31, 2018·Current Osteoporosis Reports·Fjola JohannesdottirMary L Bouxsein
Dec 5, 2018·Endocrinology and Metabolism·A Ram Hong, Sang Wan Kim
Nov 6, 2018·Medicine and Science in Sports and Exercise·Robert U NewtonDennis R Taaffe
Dec 12, 2019·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Stuart J WardenRobyn K Fuchs
Nov 25, 2019·Current Osteoporosis Reports·Behzad Javaheri, Andrew A Pitsillides
Sep 10, 2019·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Chris HartleyKatherine Brooke-Wavell
Aug 30, 2018·Current Osteoporosis Reports·Graham Treece, Andrew Gee
Mar 14, 2017·Climacteric : the Journal of the International Menopause Society·R M Daly
Jun 17, 2020·Therapeutic Advances in Musculoskeletal Disease·Ole Kristoffer OlstadKaare Morten Gautvik
Mar 10, 2017·BoneKEy Reports·Jonathan Reeve
Jan 31, 2017·Current Osteoporosis Reports·Robyn K FuchsStuart J Warden
Jun 19, 2018·Sports·Amy T Harding, Belinda R Beck
Mar 14, 2018·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·L B McMillanD Scott
Aug 27, 2017·Current Osteoporosis Reports·Jillian M Clark, David M Findlay
Jun 27, 2019·Annals of Biomedical Engineering·Julio Carballido-GamioXiaoguang Cheng
Jun 18, 2017·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·T H SuominenH Suominen
Jun 20, 2018·Scientific Reports·T D TurmezeiK E S Poole
Mar 21, 2018·Scientific Reports·Nathaniel NarraJari Hyttinen
Oct 6, 2020·Clinical Obstetrics and Gynecology·Marcus MuñozAmal Shibli-Rahhal
Nov 8, 2020·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·C-A NgD Scott
Nov 17, 2020·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·J DuV V Silberschmidt
Mar 19, 2021·Journal of Bone Metabolism·Maureen C AsheLora M Giangregorio

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
Tristan WhitmarshKenneth E Poole
Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
Kenneth E PooleCesar Libanati
Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
Jian ShenOsteoporotic Fractures in Men MrOS Research Group
© 2022 Meta ULC. All rights reserved