The influence of laser radiation of the infrared range with a wavelength of 1270 nm on mice Balb/cNude

Voprosy kurortologii, fizioterapii, i lechebnoĭ fizicheskoĭ kultury
D R DolgovaA B Peskov

Abstract

The effects of low-intensity laser radiation (LILR) on the skin depend on the wavelength and density of the irradiation flux. Moreover, the vast receptor field of the skin facilitates the systemic influence of irradiation on the body. The objective of the present study was to evaluate the effects of low-intensity laser irradiation (LIRI) of the infrared range with a wavelength of 1270 nm on the skin of mice Balb/cNude. The study was carried out with the use of the linear immunodeficient mice Balb/c nude obtained from the animal house of the Pushchino branch of the Academicians M.M. Shemyakin and Yu.A. Ovchinnikov Institute of Biorganic Chemistry. The animals were irradiated once with a fiber laser of stimulated Raman scattering with a wavelength (λ) of 1270 nm, a power of 1.96 mW during the 2 min exposure at an intensity of 10 mW/cm2, and an energy flux density of 1.2 J/cm2. The histological studies and morphometry of the skin autoptate were performed. In adition, the expression of microRNA-21, -31, -130a, -191, -200c, -205, -218 was determined in the skin. Reverse transcription and real-time PCR reactions with Taq-Man probes and primers were performed on the nucleic acid amplifier CFX96 ('BioRad', USA).MicroRNA-191 was chosen ...Continue Reading

References

Jul 10, 2012·The Journal of Biological Chemistry·Irena PastarMarjana Tomic-Canic
Apr 5, 2013·Journal of Biomedical Research·Yang XuDan Luo
Nov 23, 2013·Cancer Letters·Xiangling FengYaguang Xi
Dec 18, 2013·Scientific Reports·S G SokolovskiE U Rafailov
Jul 30, 2014·Archives of Biochemistry and Biophysics·Muhammad Nauman AftabRanjan J Perera
Jan 23, 2016·Lasers in Medical Science·Yury V SaenkoAndrey Kurkov

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