PMID: 25749515Mar 10, 2015Paper

The influence of marital status on stage at diagnosis and survival of patients with colorectal cancer

Oncotarget
Qingguo LiSanjun Cai

Abstract

Marital status was found to be an independent prognostic factor for survival in various cancer types, but it hasn't been fully studied in colorectal cancer (CRC). The Surveillance, Epidemiology and End Results database was used to compare survival outcomes with marital status in each stage. In total, 112, 776 eligible patients were identified. Patients in the widowed group were more frequently elderly women, more common of colon cancer, and more stage I/II in tumor stage (P < 0.001), but the surgery rate was comparable to that for the married group (94.72% VS 94.10%). Married CRC patients had better 5year cause-specific survival (CSS) than those unmarried (P < 0.05). Further analysis showed that widowed patients always presented the lowest CSS compared with that of other' group. Widowed patients had 5% reduction 5-year CSS compared with married patients at stage I (94.8% vs 89.8%, P < 0.001), 9.4% reduction at stage II (85.9% vs 76.5%, P < 0.001), 16.7% reduction at stage III (70.6% vs 53.9%, P < 0.001) and 6.2% reduction at stage IV(14.4% VS 8.2%, P < 0.001). These results showed that unmarried patients were at greater risk of cancer specific mortality. Despite favorable clinicpathological characteristics, widowed patients wer...Continue Reading

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Citations

Dec 20, 2016·European Psychiatry : the Journal of the Association of European Psychiatrists·P Fusar-PoliP McGuire
Aug 5, 2016·Oncotarget·Xing-Kang HeLei-Min Sun
Mar 17, 2018·International Journal of Colorectal Disease·Yang FengSanjun Cai
Feb 1, 2017·Scientific Reports·Wenjie ZhangBeicheng Sun
Oct 3, 2018·The International Journal of Health Planning and Management·Mo ChenZheng Wang
Oct 30, 2015·Journal of Gastroenterology and Hepatology·Rongping ZhouJun Li
Jun 18, 2017·Biomarkers in Medicine·Xiaomei LiuYing Wang
Jun 23, 2018·International Journal of Colorectal Disease·Dakui LuoXinxiang Li
Nov 2, 2019·Digestive Diseases and Sciences·Xiaoyuan BianLanjuan Li
Mar 19, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Albert AlhatemDebra Heller
Sep 14, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Austin B GardnerJohn K Chan
Nov 22, 2017·Oncotarget·Tingru MiaoDingguo Yao
Jan 19, 2019·International Journal of Environmental Research and Public Health·Sayaf H AlshareefNoël C Barengo
Jun 7, 2016·Cancer Medicine·Jie-Jie JinYa-Nong Wang

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