The influence of polycyclic aromatic hydrocarbons on lung function in a representative sample of the Canadian population

Environmental Pollution
Sabit CakmakRobert E Dales

Abstract

We investigated the associations between exposure to polycyclic aromatic hydrocarbons (PAHs) and selected respiratory physiologic measures in cycles 2 and 3 of the Canadian Health Measures Survey, a nationally representative population sample. Using generalized linear mixed models, we tested the association between selected PAH metabolites and 1-second forced expiratory volume (FEV1), forced vital capacity (FVC), and the ratio between the two (FEV1/FVC) in 3531 people from 6 to 79 years of age. An interquartile change in urinary PAH metabolite was associated with significant decrements in FEV1 and FVC for eight PAHs, 2-hydroxynapthalene, 1-, and 2-hydroxyphenanthrene, 2-, 3-, and 9-hydroxyfluorene and 3- and 4-hydroxyphenanthrene. Exposure to PAH may negatively affect lung function in the Canadian population.

Citations

Nov 28, 2018·Journal of Applied Microbiology·M YousefiH Hosseini
Feb 19, 2020·Journal of Exposure Science & Environmental Epidemiology·Jennifer L A KeirPaul A White
Sep 9, 2020·Archives of Environmental Contamination and Toxicology·Jinye HuQian Wu
Jul 5, 2019·Environmental Science and Pollution Research International·Maribel Rodríguez-AguilarRogelio Flores-Ramírez
Nov 15, 2019·International Journal of Environmental Health Research·Hongxuan KuangRuifang Fan
Jul 31, 2020·Environmental Science and Pollution Research International·Shih-Chang HsuChin-Wang Hsu
Jul 4, 2020·Environmental Health : a Global Access Science Source·Limin CaoWeihong Chen
Jul 16, 2021·Environmental Science and Pollution Research International·Alejandra Abigail Berumen-RodríguezRogelio Flores-Ramírez
May 24, 2018·Environmental Science & Technology·Jia-Yong LaoEddy Y Zeng
Aug 27, 2021·Journal of Health & Pollution·Chinemerem C NwaozuzuStephen O Abah
Jan 14, 2020·Ecotoxicology and Environmental Safety·Wenjuan WangAihua Zhang

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