PMID: 9170764Jun 1, 1997Paper

The influence of psychological distress on use of genetic testing for cancer risk

Journal of Consulting and Clinical Psychology
Caryn LermanH Lynch

Abstract

The recent identification of BRCA1, a breast cancer susceptibility gene, offers an unprecedented opportunity for high-risk individuals to learn whether they are genetically predisposed to develop breast or ovarian cancer. This study examined the relationships between psychological distress and use of BRCA1 testing by 149 high-risk individuals from hereditary cancer families. After a baseline assessment of demographics, objective risk, cancer-specific distress, and global distress (depressive symptoms), study participants were offered the opportunity to receive genetic counseling and to learn whether they carry a mutation in the BRCA1 gene. Overall, 58% of study participants requested BRCA1 test results, and 42% declined to learn their genetic status. After controlling for demographic factors and risk status, cancer-specific distress was significantly and positively related to BRCA1 test use, whereas global distress was unrelated to test use.

Citations

Oct 29, 2003·Journal of Psychosomatic Research·Mary Jane EsplenJiahui Wong
Feb 5, 2004·Social Science & Medicine·Catharine WangS D Sofia D Merajver
Feb 13, 2001·Patient Education and Counseling·K P TercyakC Lerman
May 1, 1999·Seminars in Oncology Nursing·P T Rieger, R D Pentz
Oct 12, 2002·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·B MeiserK Tucker
Jan 8, 2004·Psychosomatics·Nangel M Lindberg, David K Wellisch
Jan 1, 2005·Hereditary Cancer in Clinical Practice·Eveline BleikerNeil Aaronson
Nov 10, 2000·Journal of Medical Genetics·K A MetcalfeS A Narod
Oct 27, 2004·British Journal of Cancer·M WatsonUNKNOWN Psychosocial Study Collaborators
Dec 8, 2004·British Journal of Cancer·G L GriffithUNKNOWN GenQuest Research Team
Aug 24, 2010·Journal of Psychosocial Oncology·Jakob D JensenRobert Yale
Nov 17, 2011·Genetic Testing and Molecular Biomarkers·Diana L Jones, Ellen W Clayton
Mar 20, 2002·Cancer Practice·A Y KinneyR S Sandler
May 12, 2001·The Breast Journal·Patricia A. Ganz
May 14, 2004·Genetic Testing·Starlene LoaderPeter T Rowley
Sep 7, 2002·Genetic Testing·Celette Sugg SkinnerBarbara K Rimer
Mar 20, 2002·Cancer Practice·M A DiefenbachL Brower

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