The Influence of Psychological Stress on the Initiation and Progression of Diabetes and Cancer

International Journal of Endocrinology and Metabolism
Reza AfrishamDamoon Ashtary-Larky

Abstract

Psychological stress can be considered a risk factor for the initiation and progression of many pathological conditions, including type 1 and 2 diabetes mellitus and cancer. The aim of this review article was to evaluate the molecular and cellular mechanisms linking psychological stress to the onset and progression of diabetes and cancer. The current review was conducted to survey and analyze studies related to the effects of psychological stress on diabetes and cancer. Psychological stress may make individuals prone to the development of diabetes through the impairment of the hypothalamic-pituitary-adrenal (HPA) axis function, sympathetic nerves system (SNS), lipid profile, cytokines balance, renin-angiotensin system (RAS), and insulin signaling pathway. Additionally, psychological stress can contribute to the development of cancer through the perturbation in the HPA axis, SNS function, and cytokines balance. Psychological stress is also capable of decreasing the levels of oxytocin and dopamine, leading to an increased risk of cancer in susceptible individuals. It seems that psychological stress plays a significant role in the onset and progression of diabetes and cancer. The identification of the pathways triggered by psychol...Continue Reading

References

Dec 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·L F AllenS Cotecchia
Mar 1, 1994·Diabetologia·E MobergU Adamson
Jan 15, 1998·Journal of the National Cancer Institute·B L AndersenR Glaser
Mar 13, 1999·Annual Review of Psychology·A Baum, D M Posluszny
Nov 21, 2001·Nature Reviews. Molecular Cell Biology·J L Tilly
Dec 13, 2003·The Journal of Clinical Endocrinology and Metabolism·G ArnaldiM Boscaro
Mar 19, 2004·Cardiovascular Diabetology·R U PliquettR Paschke
Sep 15, 2004·Circulation·Abhiram Prasad, Arshed A Quyyumi
Oct 16, 2004·Circulation Research·Philip J BarterAlan M Fogelman
Jan 29, 2005·Diabetes Care·Anneli SepaJohnny Ludvigsson
Jul 29, 2005·The Proceedings of the Nutrition Society·D I ShawC M Williams
Nov 18, 2005·Cancer Chemotherapy and Pharmacology·Stella Maris VázquezIsabel Alicia Lüthy
Jan 24, 2006·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Anil K SoodSteven W Cole
Feb 25, 2006·Nature Reviews. Cancer·Michael H AntoniAnil K Sood
Aug 25, 2007·The Journal of Biological Chemistry·Monique B NilssonAnil K Sood
Oct 11, 2007·JAMA : the Journal of the American Medical Association·Sheldon CohenGregory E Miller
Apr 25, 2008·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Kou QinNevin A Lambert
Jun 19, 2008·Journal of Endocrinological Investigation·K KaravanakiC Dacou-Voutetakis
Jul 8, 2008·British Journal of Pharmacology·A BruzzoneI A Lüthy
Dec 3, 2008·Archives of General Psychiatry·Nicole VogelzangsBrenda W J H Penninx
Apr 4, 2009·Nature Reviews. Cancer·Frances Balkwill
Mar 20, 2010·Breast Cancer Research and Treatment·Ming ShiNing Guo
Mar 26, 2010·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Tasnim Ara, Yves A Declerck
Apr 15, 2010·The Journal of Clinical Investigation·Anil K SoodSusan K Lutgendorf
May 15, 2010·American Journal of Public Health·Mark P Petticrew, Kelley Lee
Jul 29, 2010·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·B NowotnyJ Kruse
Oct 29, 2010·American Journal of Physiology. Renal Physiology·Michael Groeschel, Branko Braam
Jan 15, 2011·Nature Reviews. Immunology·Marc Y Donath, Steven E Shoelson
Nov 1, 2011·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·N S Kalupahana, N Moustaid-Moussa
Aug 1, 2012·Stress : the International Journal on the Biology of Stress·Sandor SzaboArpad Somogyi
Jan 31, 2013·Nature Communications·Guillermo N Armaiz-PenaAnil K Sood
Mar 23, 2013·Journal of Translational Medicine·Soraya L VallesJosé M Estrela
Jun 10, 2014·Lancet·Yuankai Shi, Frank B Hu

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Citations

Nov 13, 2019·Current Diabetes Reviews·Vivek Kumar Sharma, Thakur Gurjeet Singh
Oct 17, 2019·Journal of Clinical Medicine·Stavroula BaritakiCharalabos Pothoulakis
Dec 10, 2019·Oxidative Medicine and Cellular Longevity·Joanna KrukMagdalena Gronostaj
Dec 3, 2020·Frontiers in Psychiatry·Alison Accarie, Tim Vanuytsel
Mar 16, 2021·Journal of Epidemiology·Rand JarrochJussi Kauhanen
Jun 3, 2021·International Journal of Molecular Sciences·Yangyang HePia-Maria Wippert

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