The influence of radioisotope vehicle on breast sentinel node detection

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
T JastrzebskiA Kopacz

Abstract

To assess the relationship between carrier molecule size and time elapsing between marker injection and sentinel node(s) biopsy in patients with breast cancer. The study performed on 122 women, in whom the sentinel node(s) was identified according to the procedure described below. In Group I (n=72 patients), SN identification was done with radioisotope marker of 400-3000 nm molecule size (tin colloid). In Group II (n=50 patients) radioisotope marker of <100 nm molecule size (colloidal albumin) was used. All the patients of both groups received the markers with a single-point, intradermal, periareolar injection. Four hours after the injection (Group I - surgery in the next day) or immediately before the surgery (in this same day) (Group II), stationary lymphoscintigraphy was performed. Mean numbers of sentinel nodes identified with the radioisotope method in Groups I and II were 1.22 and 1.48, respectively. The difference was statistically significant (p<0.01). There is a relationship between the radioisotope marker molecule size and the injection-to-intra-operative evaluation time. Administration of small molecule size radioisotope marker several hours prior to the planned surgery appears to be the optimum procedure in this met...Continue Reading

References

Apr 3, 1999·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·F W van der EntA G Hoofwijk
May 15, 2001·The British Journal of Surgery·T WatanabeS Takenoshita
Jun 13, 2001·Journal of the American College of Surgeons·S L WongK M McMasters
Feb 7, 2002·Annals of Surgical Oncology·Todd M TuttleKelly M McMasters
Jun 8, 2002·Annals of Surgical Oncology·May Lynn QuanJ Gregory McKinnon
Oct 23, 2002·The British Journal of Surgery·M T NanoM Bochner
Dec 13, 2002·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·E LeppänenK von Smitten
Apr 5, 2003·European Journal of Nuclear Medicine and Molecular Imaging·S MirzaeiG A Jánoki
Aug 9, 2003·The New England Journal of Medicine·Umberto VeronesiRoberto Gennari
Jan 28, 2004·Annals of Surgery·Susanne H EstourgieBin B R Kroon
Mar 11, 2004·The Breast Journal·Richard L EllisGary L Dunnington
May 29, 2004·Annals of Surgery·Rakhshanda LayeequeV Suzanne Klimberg
Jun 5, 2004·The Breast : Official Journal of the European Society of Mastology·M MersonC Tondini
Aug 7, 2004·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·B van der VegtJ de Vries
Aug 25, 2004·The Breast : Official Journal of the European Society of Mastology·K J P van Wessem, W S Meijer
Nov 5, 2004·Annals of Surgical Oncology·Lucio FortunatoCarlo Eugenio Vitelli
Mar 23, 2005·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·M C KokkeK Bosscha
Mar 26, 2005·European Journal of Nuclear Medicine and Molecular Imaging·A H ChakeraB Hesse

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Citations

Aug 12, 2010·European Journal of Nuclear Medicine and Molecular Imaging·Gang ChengAbass Alavi
May 3, 2011·Journal of Controlled Release : Official Journal of the Controlled Release Society·M VisscherH Rogalla

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