The Influence of Selective Laser Melting (SLM) Process Parameters on In-Vitro Cell Response

International Journal of Molecular Sciences
Bartłomiej WysockiWojciech Święszkowski

Abstract

The use of laser 3D printers is very perspective in the fabrication of solid and porous implants made of various polymers, metals, and its alloys. The Selective Laser Melting (SLM) process, in which consolidated powders are fully melted on each layer, gives the possibility of fabrication personalized implants based on the Computer Aid Design (CAD) model. During SLM fabrication on a 3D printer, depending on the system applied, there is a possibility for setting the amount of energy density (J/mm³) transferred to the consolidated powders, thus controlling its porosity, contact angle and roughness. In this study, we have controlled energy density in a range 8⁻45 J/mm³ delivered to titanium powder by setting various levels of laser power (25⁻45 W), exposure time (20⁻80 µs) and distance between exposure points (20⁻60 µm). The growing energy density within studied range increased from 63 to 90% and decreased from 31 to 13 µm samples density and Ra parameter, respectively. The surface energy 55⁻466 mN/m was achieved with contact angles in range 72⁻128° and 53⁻105° for water and formamide, respectively. The human mesenchymal stem cells (hMSCs) adhesion after 4 h decreased with increasing energy density delivered during processing withi...Continue Reading

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Citations

Jan 4, 2019·Advanced Healthcare Materials·Wujin SunAli Khademhosseini
Apr 9, 2020·Frontiers in Pharmacology·Daoyang FanZhongjun Liu
Nov 23, 2019·Materials Science & Engineering. C, Materials for Biological Applications·Ziyu ChenHang Fang
Feb 11, 2019·ACS Biomaterials Science & Engineering·Yu GuoYongqiang Hao
Jul 13, 2021·Journal of Materials Research·Georges E DaoudKyle K VanKoevering

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Methods Mentioned

BETA
chemical treatments
thermal treatments
chemical treatment
X-ray
Assay

Software Mentioned

SLM
KyPlot
Advantage based data system

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