The influence of sperm motility and cryopreservation on the treatment outcome after intracytoplasmic sperm injection following testicular sperm extraction

Acta Obstetricia Et Gynecologica Scandinavica
Marloes HesselLiliana Ramos

Abstract

It is already known that embryo quality is a major contributing factor to the outcome of assisted reproduction techniques. This study focuses on treatment variables that might be of importance to the outcome of intracytoplasmic sperm injection following testicular sperm extraction (TESE-ICSI) in non-obstructive azoospermia. A retrospective cohort study was conducted at a Dutch tertiary care academic training hospital between July 2009 and December 2013. With logistic regression analysis we explored the influence of treatment variables, including testicular sperm parameters - (i) motile or tail touch spermatozoa, and (ii) use of fresh or frozen testicular semen-samples - on biochemical and ongoing pregnancy rates after single (n = 393) and double embryo transfer (n = 352). Multivariate logistic regression analysis identified the rank of the TESE-ICSI attempt [odds ratio (OR) 0.8, 95% confidence interval (95% CI) 0.70-0.93], the number of embryos available for transfer (OR 1.1, 95% CI 1.06-1.19) and quality of the embryo(s) transferred (OR 12.8, 95% CI 5.00-32.67) as possible predictors of biochemical pregnancy, whereas only embryo quality (OR 16.9, 95% CI 5.23-54.87) was independently associated with ongoing pregnancy. The use o...Continue Reading

References

Jul 15, 1998·Human Reproduction·D S Irvine
Nov 1, 2000·Human Reproduction·U I Ezeh
Jan 10, 2001·Current Opinion in Urology·P T Chan, P N Schlegel
Nov 16, 2004·Andrologia·T M AktanT Yurdakul
Aug 9, 2008·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Janos KoncSandor Cseh
Aug 1, 2009·Urology·Sergey I MoskovtsevJ Brendan M Mullen
Jun 29, 2010·Human Reproduction Update·L L van LoenderslootF van der Veen
Aug 6, 2011·Human Reproduction Update·C OrtegaH Tournaye
May 18, 2012·European Urology·Andreas JungwirthUNKNOWN European Association of Urology Working Group on Male Infertility
Dec 25, 2012·Fertility and Sterility·Marie WalschaertsPatrick Thonneau

❮ Previous
Next ❯

Citations

Mar 12, 2016·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Igna F ReijndersKathrin Fleischer
Jul 14, 2016·Human Reproduction·A M MeijerinkL Ramos
Apr 6, 2017·Human Reproduction Update·Giovanni CoronaUNKNOWN Klinefelter ItaliaN Group (KING)
Apr 22, 2017·Clinical and Experimental Reproductive Medicine·Huanhua ChenXianyou Gan
Sep 20, 2017·Reproductive Biology and Endocrinology : RB&E·Huanhua ChenYingqin Huang
Dec 10, 2020·The Journal of Clinical Endocrinology and Metabolism·Aditi SharmaChanna N Jayasena
Mar 9, 2021·Andrologia·Chara OraiopoulouAlexia Chatziparasidou

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.