The Influence of the Gut Microbiome on Obesity in Adults and the Role of Probiotics, Prebiotics, and Synbiotics for Weight Loss

Preventive Nutrition and Food Science
Antoine AounNatacha Hamod

Abstract

The link between the gut microbiome and obesity is not well defined. Understanding of the role of the gut microbiome in weight and health management may lead to future revolutionary changes for treating obesity. This review examined the relationship between obesity and the gut microbiome, and the role of probiotics, prebiotics, and synbiotics for preventing and treating obesity. We used PubMed and Google Scholar to collect appropriate articles for the review. We showed that the gut microbiome has an impact on nutrient metabolism and energy expenditure. Moreover, different modalities of obesity treatment have been shown to change the diversity and composition of the gut microbiome; this raises questions about the role these changes may play in weight loss. In addition, studies have shown that supplementation with probiotics, prebiotics, and synbiotics may alter the secretion of hormones, neurotransmitters, and inflammatory factors, thus preventing food intake triggers that lead to weight gain. Further clinical studies are needed to better understand how different species of bacteria in the gut microbiome may affect weight gain, and to determine the most appropriate doses, compositions, and regimens of probiotics, prebiotics, and...Continue Reading

Citations

Jan 19, 2021·Beneficial Microbes·X M Tomé-CastroP Roman
Dec 6, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Adrian Eugen RoscaAna-Maria Zagrean
May 1, 2021·International Journal of Environmental Research and Public Health·Francesc Xavier MedinaAlicia Aguilar-Martínez
Apr 17, 2021·Current Opinion in Clinical Nutrition and Metabolic Care·Omar Ramos-LopezUNKNOWN Collaborators: Rodrigo San-Cristobal and Maria P. Portillo
Jul 31, 2021·Journal of Hazardous Materials·K B ArunAshok Pandey
Aug 5, 2021·Trends in Food Science & Technology·Gitishree DasJayanta Kumar Patra
Aug 28, 2021·Nutrients·Maria Letizia PetroniFederico Ravaioli
Oct 31, 2021·Archives of Disease in Childhood·Laura DiamondShaun K Morris

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