The influence of urinary flow rate on mercury excretion in children.

Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)
Felicia TrachtenbergSonja McKinlay

Abstract

There is limited literature concerning the effect of urinary flow rate on mercury excretion at low-level exposure. The aim of the present study is to examine the influence of urinary flow rate on mercury excretion in children. Also of interest is the influence of flow rate on creatinine excretion and creatinine-corrected mercury, which arisearises with spot urine samples. A substudy of the New England Children's Amalgam Trial collected pairs of urine samples from children aged 10-16 years: a timed overnight collection and a spot daytime sample collected the following day. These samples were analyzed for mercury and creatinine concentration. Regression analysis was used to model the effect of urinary flow rate in the timed overnight samples. A paired t-test compared concentrations and creatinine-corrected mercury between overnight and daytime samples. Creatinine excretion rate (mg/h) increased significantly with urinary flow rate (mL/h), whereas creatinine concentration (g/L) decreased with flow rate. We found a non-significant increase in mercury excretion rate (ng/h) with flow rate, and mercury concentration decreased with flow rate. Mercury and creatinine concentrations were significantly higher in the overnight compared to d...Continue Reading

References

Sep 19, 1975·International Archives of Occupational and Environmental Health·J K PiotrowskiE M Mogilnicka
Oct 1, 1989·Journal of Occupational Medicine. : Official Publication of the Industrial Medical Association·G N Greenberg, R J Levine
Oct 1, 1993·American Industrial Hygiene Association Journal·M F BoenigerJ Rosenberg
Feb 9, 2002·Environmental Health Perspectives·Thomas W Clarkson
Dec 10, 2003·Controlled Clinical Trials·UNKNOWN Children's Amalgam Trial Study Group
Apr 20, 2006·JAMA : the Journal of the American Medical Association·David C BellingerSonja McKinlay

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Citations

Jun 10, 2011·International Archives of Occupational and Environmental Health·Magnus AkerstromGerd Sallsten
Aug 30, 2013·Journal of Occupational Medicine and Toxicology·Daniel J DuttonJc Herbert Emery
Sep 19, 2015·Annals of Human Biology·Margarita G SkalnayaAnatoly V Skalny
Jul 26, 2011·The Science of the Total Environment·G M RichardsonJ Gravière
May 24, 2011·The Science of the Total Environment·Iman Al-Saleh, Al Anoud Al-Sedairi
Dec 21, 2010·Analytica Chimica Acta·D RyanMegan Kendall
Jun 12, 2012·The Science of the Total Environment·Iman Al-SalehRola Elkhatib
Jan 22, 2019·Journal of Korean Medical Science·Edward Barroga, Hiroshi Mitoma
Sep 25, 2010·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Felicia TrachtenbergSonja McKinlay
Jun 9, 2018·Journal of Exposure Science & Environmental Epidemiology·Susan MacPhersonMandy Fisher
Mar 1, 2012·Annals of Clinical Biochemistry·Christine E SieniawskaValerie Walker

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