The influence of zygosity status on blood pressure and on lipid profiles in male and female twins

Journal of Hypertension
Pernille PoulsenH Beck-Nielsen

Abstract

To study the influence of zygosity on blood pressure and serum lipid concentrations among male and female twins. Department of Endocrinology, Odense University Hospital, Denmark. A total of 125 monozygotic and 178 dizygotic twin pairs aged 55-74 years of age, ascertained from The Danish Twin Register. Population-based cross-sectional study. Blood pressure and serum lipid concentrations. The prevalence of hypertriglyceridemia and hypercholesterolemia were higher among monozygotic compared with dizygotic twins, whereas the prevalence of hypertension was similar. The level of triglycerides [0.28 (0.44) versus 0.18 (0.41), P = 0.01] and total cholesterol [1.82 (0.17) versus 1.78 (0.19), P = 0.03] were significantly higher in monozygotic compared with dizygotic twins. Systolic blood pressure was non-significantly higher among monozygotic twins (136.8 (21.3) versus 134.1 (19.6), P = 0.10). When comparing monozygotic and dizygotic twins within each sex group, the difference in triglyceride level was only apparent among male twins and the differences in systolic blood pressure and total cholesterol were only seen among female twins. Birth weight as determined in a subgroup of the population was similar in monozygotic and dizygotic twin...Continue Reading

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Citations

Jan 27, 2005·Paediatric and Perinatal Epidemiology·Ruth Morley
Jan 29, 2011·The Journal of Clinical Hypertension·Joel Handler
Dec 22, 2005·Seminars in Fetal & Neonatal Medicine·Ruth Morley
Aug 19, 2007·Current Opinion in Clinical Nutrition and Metabolic Care·Allan Vaag, Pernille Poulsen
Mar 5, 2005·Reproduction, Fertility, and Development·Michael J Davies
Mar 25, 2017·International Journal of Epidemiology·Karri SilventoinenJaakko Kaprio

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