The influences of propranolol on serum gastrin concentration and hydrochloric acid secretion in response to hypoglycemia in normal subjects

Digestion
H KaessM Dŏrner

Abstract

In ten normal subjects the effect of propranolol on serum gastrin concentration and HC1 secretion during insulin hypoglycemia (0.2 U/kg) was studied. Under the influence of propranolol (50 mug/kg intravenously in 3 min) the gastrin response to insulin was abolished. The insulin-induced HC1 secretion was reduced by propranolol from 38 to 18 mEq/2h (p less than 0.01). These results are compatible with the hypothesis of beta-adrenergic stimulation on serum gastrin concentration and HC1 secretion during insulin hypoglycemia.

Citations

Jan 1, 1981·Digestive Diseases and Sciences·V RaynerJ B Bruce
May 1, 1983·World Journal of Surgery·J JärhultB Hamberger
Jan 17, 1983·Life Sciences·C BekkerL Christiansen
Dec 1, 1977·European Journal of Clinical Investigation·O BrandsborgN J Christensen
Feb 1, 1978·European Journal of Clinical Investigation·O BrandsborgN J Christensen
Jan 1, 1979·Scandinavian Journal of Gastroenterology·J Järhult, K Uvnäs-Wallensten
Jul 1, 1980·Gut·P T ReganE P DiMagno
Sep 1, 1978·Scandinavian Journal of Clinical and Laboratory Investigation·O BrandsborgN A Løvgreen

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