The Information Technology Infrastructure for the Translational Genomics Core and the Partners Biobank at Partners Personalized Medicine

Journal of Personalized Medicine
Natalie BoutinMatilde Vickers

Abstract

The Biobank and Translational Genomics core at Partners Personalized Medicine requires robust software and hardware. This Information Technology (IT) infrastructure enables the storage and transfer of large amounts of data, drives efficiencies in the laboratory, maintains data integrity from the time of consent to the time that genomic data is distributed for research, and enables the management of complex genetic data. Here, we describe the functional components of the research IT infrastructure at Partners Personalized Medicine and how they integrate with existing clinical and research systems, review some of the ways in which this IT infrastructure maintains data integrity and security, and discuss some of the challenges inherent to building and maintaining such infrastructure.

Citations

Mar 2, 2016·Journal of Personalized Medicine·Scott T Weiss, Meini Sumbada Shin
Apr 25, 2012·Computer Methods and Programs in Biomedicine·Dario SalviSergio Salvi
Sep 24, 2016·Journal of Personalized Medicine·Scott T Weiss
Mar 25, 2017·Biopreservation and Biobanking·Tanja MacheinerKarine Sargsyan
Sep 12, 2018·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·Blaike M DumasRami R Hallac
Jun 29, 2021·Biosafety and Health·Julie RouxZisis Kozlakidis
Jul 3, 2021·Healthcare·Margareth TimóteoGutemberg Alves
Oct 6, 2021·Journal of the American Medical Informatics Association : JAMIA·Harrison G ZhangTianxi Cai

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Methods Mentioned

BETA
genotyping

Software Mentioned

STARLIMS
STARLIMS Gateway for Integrated Genomic - Proteomic Applicatio...
i2b2
Constrack
GIGPAD
Epic
Crimson

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