Get paper from

journal cover

The inherent mutational tolerance and antigenic evolvability of influenza hemagglutinin

bioRxiv

May 12, 2014

Bargavi Thyagarajan, Jesse D. Bloom

Get paper from

Abstract

Influenza is notable for its evolutionary capacity to escape immunity targeting the viral hemagglutinin. We used deep mutational scanning to examine the extent to which a high inherent mutational tolerance contributes to this antigenic evolvability. We created mutant viruses that incorp...read more

Mentioned in this Paper

Amino Acid [EPC]
Mutant
Scanning
Mutation Abnormality
Influenza virus vaccine
Passage Tissue Culture Technique
Tissue Culture
Site
Virus
Hemagglutinin
3
1
Paper Details
References
    • References
    • Citations

      References currently unavailable

      We're still populating references for this paper, please check back later.
    • References
    • Citations

      No citations available

      This paper may not have been cited yet.
  • The inherent mutational tolerance and antigenic evolvability of influenza hemagglutinin

    bioRxiv

    May 12, 2014

    Bargavi Thyagarajan, Jesse D. Bloom

    PMID: 990005041

    DOI: 10.1101/005041

    Abstract

    Influenza is notable for its evolutionary capacity to escape immunity targeting the viral hemagglutinin. We used deep mutational scanning to examine the extent to which a high inherent mutational tolerance contributes to this antigenic evolvability. We created mutant viruses that incorp...read more

    Mentioned in this Paper

    Amino Acid [EPC]
    Mutant
    Scanning
    Mutation Abnormality
    Influenza virus vaccine
    3
    1
    Paper Details
    References
    • References
    • Citations

      References currently unavailable

      We're still populating references for this paper, please check back later.
    • References
    • Citations

      No citations available

      This paper may not have been cited yet.
  • Get paper from

    © 2019 Meta ULC. All rights reserved.
    /papers/the-inherent-mutational-tolerance-and-antigenic/990005041