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The inhibitory effect of actinomycin D and cycloheximide on the increase in activity of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in experimentally induced diseased skeletal muscles

The Histochemical Journal

Sep 1, 1984

A E Meijer, E A Elias

PMID: 6480400

Abstract

The myotoxic effect of the subcutaneous administration of N,N1-dimethyl-p-phenylenediamine (DPPD) in rats was enhanced by the simultaneous administration of hyaluronidase. The resulting myopathy was associated with an early and dramatic increase in activity of glucose-6-phosphate dehydr...read more

Mentioned in this Paper

Pentose Phosphate Pathway
RNA Chemical Synthesis
Enzymes, antithrombotic
August Rats
Phenylenediamines
N, N'-diphenyl-4-phenylenediamine
Myopathy
dimethyl-4-phenylenediamine hydrochloride
Protein Biosynthesis
Glucosephosphate Dehydrogenase
Paper Details
References
  • References17
  • Citations5
12
  • References17
  • Citations5

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The inhibitory effect of actinomycin D and cycloheximide on the increase in activity of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in experimentally induced diseased skeletal muscles

The Histochemical Journal

Sep 1, 1984

A E Meijer, E A Elias

PMID: 6480400

DOI:

Abstract

The myotoxic effect of the subcutaneous administration of N,N1-dimethyl-p-phenylenediamine (DPPD) in rats was enhanced by the simultaneous administration of hyaluronidase. The resulting myopathy was associated with an early and dramatic increase in activity of glucose-6-phosphate dehydr...read more

Mentioned in this Paper

Pentose Phosphate Pathway
RNA Chemical Synthesis
Enzymes, antithrombotic
August Rats
Phenylenediamines
N, N'-diphenyl-4-phenylenediamine
Myopathy
dimethyl-4-phenylenediamine hydrochloride
Protein Biosynthesis
Glucosephosphate Dehydrogenase

Related Papers

Journal of Molecular and Cellular Cardiology

Lysosomal enzyme release in the isolated perfused heart of immunized rats

Journal of Molecular and Cellular CardiologyNovember 1, 1977
M Fields, A Laufer
Journal of Neurology

Additional biochemical criteria in the differential diagnosis of myositis

Journal of NeurologyDecember 1, 1987
C W ZimmermannJ Peiffer
Paper Details
References
  • References17
  • Citations5
12
  • References17
  • Citations5
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