The interaction between casein micelles and gold nanoparticles

Journal of Colloid and Interface Science
Yan Liu, Rong Guo

Abstract

For the first time, the interaction of casein micelle (CM) with gold nanoparticles (GNPs) was studied using TEM, UV-visible, FTIR and fluorescence spectroscopy methods. The results show that GNPs bind to CM surface, leading to the formation of GNP-CM conjugates. GNPs exhibit similar particle diameters, and the CM structure is retained in GNP-CM conjugates. Furthermore, GNP-CM conjugates display good stability against salt concentration and pH. The combination of these measurements suggests that GNPs presumably bind to CM surfaces via complexation with the carboxylate or amine groups on CM surfaces, but not by electrostatic action.

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Citations

Jan 1, 2010·Biomedical Imaging and Intervention Journal·A Low, V Bansal
Dec 18, 2013·Journal of Biological Engineering·Jin Gu, Jeffrey M Catchmark
Feb 14, 2013·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Ahmed O ElzoghbyNazik A Elgindy
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May 31, 2021·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·Rana M AdelAmany S Amer
Sep 18, 2010·Analytical Chemistry·Maria A PanagopoulouMamas I Prodromidis

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