The interaction between copper and coronary risk indicators

Japanese Heart Journal
B AdamM Alvur

Abstract

We studied the effects of external copper exposure on plasma copper, serum lipids, lipoproteins and apolipoproteins in workers who have excessive contact with copper. Fifty-eight healthy Turkish males who were working in the copper processing industry and 33 control subjects were examined. Copper concentration was measured by flame atomic absorption spectrometry, lipid and lipoprotein levels were detected by spectrophotometry and apolipoproteins were measured with a nephelometer. There was no significant difference in plasma copper between the workers and the controls. However, in the worker group, the mean levels of TC, LDL-C, apoAI, apoB and Lp (a) were significantly higher while the mean level of HDL-C was significantly lower than that of the controls. In addition, there was a significant positive correlation between plasma copper and LDL-C only in the workers group. Our findings suggest that excessive contact with copper may contribute to coronary risk factors.

References

Feb 5, 1976·The New England Journal of Medicine·G G RhoadsA Kagan
May 1, 1990·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·W PalinskiJ L Witztum
Jul 1, 1991·Biological Trace Element Research·D M MedeirosL Stacy
Apr 6, 1989·The New England Journal of Medicine·D SteinbergJ L Witztum
Jan 1, 1989·Free Radical Research Communications·H EsterbauerM Rotheneder
Aug 1, 1988·American Journal of Epidemiology·F J KokH A Valkenburg
Jan 1, 1987·Annals of Nutrition & Metabolism·M BiałkowskaB Danko
Sep 1, 1985·American Journal of Epidemiology·D KromhoutR L Zielhuis

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Citations

Feb 24, 2007·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·Seyyed Mohammad Reza Kazemi-BajestaniGordon A A Ferns
Oct 26, 2005·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·Majid Ghayour-MobarhanGordon A A Ferns
Jul 31, 2020·Mini Reviews in Medicinal Chemistry·Mahsa MalekahmadiMajid Ghayour Mobarhan

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