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The interaction of antihistamines with lecithin monolayers

The Journal of Pharmacy and Pharmacology

Nov 1, 1975

David Attwood, O K Udeala

PMID: 1487

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Abstract

The interaction of a series of antihistamines with monolayers of L-alpha-dipalmitoyl lecithin has been examined. An increase in the monolayer surface pressure was noted for monolayers spread on the antihistamine solutions, suggesting penetration of the film by drug molecules. At high su...read more

Mentioned in this Paper

Membranes, Artificial
Antihistamines, Classical
Drug Interactions
Interfacial Force
Surface Properties
Phosphatidylcholines
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  • The interaction of antihistamines with lecithin monolayers

    The Journal of Pharmacy and Pharmacology

    Nov 1, 1975

    David Attwood, O K Udeala

    PMID: 1487

    DOI:

    Abstract

    The interaction of a series of antihistamines with monolayers of L-alpha-dipalmitoyl lecithin has been examined. An increase in the monolayer surface pressure was noted for monolayers spread on the antihistamine solutions, suggesting penetration of the film by drug molecules. At high su...read more

    Mentioned in this Paper

    Membranes, Artificial
    Antihistamines, Classical
    Drug Interactions
    Interfacial Force
    Surface Properties

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