The interactions between endogenous bacteria, dietary components and the mucus layer of the large bowel

Food & Function
Alicia M BarnettAdrian L Cookson

Abstract

The mucus layer covering the epithelial surface of the gastrointestinal tract serves as the front line of protection against the luminal contents and plays a key role in the establishment and activity of the commensal microbiota. The composition and complexity of the bacterial community within this environment is altered by the introduction of fermentable dietary components. These dietary components can change the metabolic end products of bacterial fermentation, which in turn are able to modify the expression of mucin genes and proteins leading to an increase in the mucus layer thickness. This review introduces some of the key interactions between fermentable carbohydrates, commensal bacteria, and intestinal cells which influence mucin production.

References

Nov 11, 1991·International Journal of Cancer. Journal International Du Cancer·T LesuffleurA Zweibaum
Jan 1, 1995·Annual Review of Physiology·G Forstner
Jan 1, 1995·Annual Review of Physiology·S J Gendler, A P Spicer
Jun 1, 1995·The Journal of Nutrition·G R Gibson, M B Roberfroid
Jan 1, 1995·Gut·I A FinnieJ M Rhodes
Jun 1, 1993·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A Lidbeck, C E Nord
May 29, 1997·International Journal of Cancer. Journal International Du Cancer·A BaruchD H Wreschner
May 1, 1997·Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie·A M Robertson, D P Wright
Nov 11, 1998·FEMS Microbiology Letters·P V KirjavainenS J Salminen
Feb 20, 1999·The Biochemical Journal·N MoniauxJ P Aubert
Jul 2, 1999·International Journal of Cancer. Journal International Du Cancer·M HartmanD H Wreschner
Jul 16, 1999·Biochemical and Biophysical Research Communications·S J WilliamsM A McGuckin
Sep 29, 1999·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·J C MeslinC Andrieux
Nov 5, 1999·The Journal of Biological Chemistry·J Perez-Vilar, R L Hill
Mar 14, 2001·The Journal of Membrane Biology·J R Pappenheimer
Mar 30, 2001·The Journal of Biological Chemistry·S J WilliamsM A McGuckin
May 9, 2001·Biochemical and Biophysical Research Communications·S ParryA Harris
May 16, 2001·Science·L V Hooper, J I Gordon
Jun 8, 2001·The American Journal of Clinical Nutrition·B Deplancke, H R Gaskins
Oct 2, 2001·Frontiers in Bioscience : a Journal and Virtual Library·A P CorfieldC S Probert
Oct 2, 2001·Frontiers in Bioscience : a Journal and Virtual Library·N MoniauxS K Batra
Apr 30, 2002·Archives of Disease in Childhood. Fetal and Neonatal Edition·G BoehmA Marini
Jun 6, 2002·European Journal of Biochemistry·Lone T PallesenJan T Rasmussen

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Citations

Jun 8, 2014·The Journal of Immunology : Official Journal of the American Association of Immunologists·Dagmara A SkoczekAnastasia Sobolewski
Jan 30, 2015·Critical Reviews in Food Science and Nutrition·L Y M WanH El-Nezami
Jan 7, 2014·Annual Review of Food Science and Technology·Anne Salonen, Willem M de Vos
Jul 25, 2018·Nutrients·Mary Ni LochlainnClaire J Steves
Mar 23, 2017·European Journal of Nutrition·Glaucia Carielo LimaMário Roberto Maróstica Junior
Sep 10, 2021·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Fuchang LiChunyang Wang

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