The Interdisciplinary Management of Newly Diagnosed Pituitary Tumors.

Deutsches Ärzteblatt International
Cornelia Jaursch-HanckeMartin Fassnacht

Abstract

The increasing use of cranial tomographic imaging has led to the more frequent discovery of pituitary tumors. In this review, we discuss the clinical symptoms that point toward a pituitary tumor, the required diagnostic studies, the potential need for follow-up studies, and the indications for neurosurgical treatment. This review is based on pertinent publications from the years 2005-2020 that were retrieved by a selective search in PubMed, as well as on the current German S2k guideline, which was created with the present authors playing a coordinating role, and on further guidelines from abroad. Relevant information from older reviews was also considered. The reported prevalence of pituitary tumors varies depending on the method of data acquisition. Autopsy studies yield a figure of 10.7%, while population-based studies reported 77.6-115.6 cases per 100 000 inhabitants. These lesions are nearly always benign, and 85% of them are pituitary adenomas. Pituitary adenomas measuring less than 1 cm in diameter are called microadenomas, while those measuring 1 cm or more are called macroadenomas. According to magnetic resonance imaging (MRI) studies, the prevalence of microadenomas in the general population is in the range of 10-38%, ...Continue Reading

References

Oct 1, 1994·The Journal of Clinical Endocrinology and Metabolism·L A KaneD Zimmerman
Aug 5, 2006·Clinical Endocrinology·Felipe F CasanuevaAndrea Giustina
Aug 26, 2006·Nature Clinical Practice. Endocrinology & Metabolism·Armand Krikorian, David Aron
Feb 9, 2007·European Journal of Endocrinology·Wolfgang SaegerStephan Petersenn
Dec 1, 2009·Best Practice & Research. Clinical Endocrinology & Metabolism·Mark E Molitch
Feb 8, 2011·The Journal of Clinical Endocrinology and Metabolism·Shlomo MelmedUNKNOWN Endocrine Society
Mar 23, 2011·Nature Reviews. Endocrinology·Shlomo Melmed
Apr 9, 2011·The Journal of Clinical Endocrinology and Metabolism·Pamela U FredaUNKNOWN Endocrine Society
Apr 24, 2012·Annales d'endocrinologie·Niki Karavitaki
Jan 9, 2013·The Journal of Clinical Endocrinology and Metabolism·Lisa ÓnnestamHelena Filipsson Nyström
Oct 8, 2013·Best Practice & Research. Clinical Endocrinology & Metabolism·Michael Fahie-Wilson, Thomas P Smith
Sep 25, 2014·Handbook of Clinical Neurology·Mark E Molitch
Jun 14, 2015·Annales d'endocrinologie·Lucie AbouafMaud Lebas
Oct 2, 2015·European Journal of Endocrinology·Tomas Thor AgustssonRafn Benediktsson
Apr 14, 2016·European Journal of Endocrinology·Vladimir VasilevAlbert Beckers
Aug 21, 2016·Neuro-oncology·Gautam U Mehta, Russell R Lonser
Oct 8, 2016·Orphanet Journal of Rare Diseases·Thierry Brue, Frederic Castinetti
Sep 29, 2017·Endocrine Connections·Enrique Soto-PedreGraham P Leese
Mar 22, 2018·The Journal of Clinical Endocrinology and Metabolism·Shalender BhasinMaria A Yialamas
Jul 28, 2018·Nature Reviews. Endocrinology·Shlomo MelmedAndrea Giustina
Apr 28, 2019·Best Practice & Research. Clinical Endocrinology & Metabolism·Cesar Luiz BoguszewskiLeandro Kasuki
Oct 31, 2019·The Journal of Clinical Endocrinology and Metabolism·German RubinsteinMartin Reincke
Mar 28, 2020·European Journal of Endocrinology·Daniela EspositoDaniel S Olsson
Jun 25, 2020·European Journal of Endocrinology·Stephanie Burger-StrittStefanie Hahner

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.