The Interest of Women with Mayer-Rokitansky-Küster-Hauser Syndrome and Laparoscopic Vecchietti Neovagina in Uterus Transplantation

Journal of Pediatric and Adolescent Gynecology
Roman ChmelJiri Fronek

Abstract

The goal of this study was to assess a group of women with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome with surgically created neovaginas in the interest of uterus transplantation (UTx) and to recruit the first group of applicants for a UTx trial. This was an original prospective study using semistructured interviews. A study group of 50 women with MRKH syndrome with Vecchietti neovaginas was recruited via letter of invitation. Interest of MRKH women in obtaining experimental UTx for the treatment of absolute uterine factor infertility. A total of 50 women responded via e-mail and 31 (62% [31 of 50] of the study group) expressed serious interest in UTx after complete information about its risks and benefits was provided during the first semistructured interview. They subsequently agreed to participate in additional interviews and further examinations. Because of various reasons, only 9 women were prepared to enter our UTx trial (18% [9 of 50] of the study group). Three recipients/donors were accepted into the living donor arm and 6 into the deceased brain donor arm of the trial. Nearly two-thirds of our MRKH syndrome study group women with surgically created neovaginas were interested in UTx and motivated to undergo this met...Continue Reading

Citations

Aug 29, 2018·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Roman ChmelJiri Fronek
May 28, 2019·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Roman ChmelJiri Fronek
Jun 24, 2020·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Roman ChmelZlatko Pastor
Mar 5, 2020·Human Reproduction Open·H E PetersW J K Hehenkamp
May 8, 2019·The Journal of Obstetrics and Gynaecology Research·Roman ChmelJiri Fronek
Feb 19, 2020·World Journal of Urology·Anne-Françoise SpinoitGunter De Win
Jan 21, 2021·JAMA Network Open·Benjamin P JonesJ Richard Smith
Apr 30, 2021·BJOG : an International Journal of Obstetrics and Gynaecology·B P JonesUNKNOWN Royal College of Obstetricians and Gynaecologists
Jul 13, 2021·The Obstetrician & Gynaecologist : the Journal for Continuing Professional Development From the Royal College of Obstetricians & Gynaecologists·Benjamin P JonesJ Richard Smith
Aug 28, 2021·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Roman ChmelRoman Chmel

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