PMID: 7337148Jan 1, 1980Paper

The interfering effect of human IgG antisperm antibodies on human sperm penetration of zona-free hamster eggs

American Journal of Reproductive Immunology : AJRI
G G HaasD P Wolf

Abstract

A liquid-phase radioimmunoassay was used to quantitate sperm-associated IgG in a population of patients with unexplained infertility. Plasma IgG antisperm antibody activity was identified in a subpopulation of these patients. Using the human sperm/hamster egg assay, a unique functional test of human sperm penetrating capacity, we identified a subset of these positive patients whose plasma significantly and reproducibly inhibited penetration. This study implies that antigen-antibody reactions may prevent sperm responses that are critical to sperm-egg fusion.

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Citations

Dec 1, 1985·Journal of in Vitro Fertilization and Embryo Transfer : IVF·T PexiederP Janecek
Jan 29, 1981·The New England Journal of Medicine
Mar 1, 1991·American Journal of Reproductive Immunology : AJRI·F FrancavillaR Santucci
Apr 1, 1996·American Journal of Reproductive Immunology : AJRI·W H KuttehB R Carr
Nov 1, 1987·The Journal of Clinical Investigation·R K Naz
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Jan 1, 1985·Archives of Andrology·L R Brannen-Brock, J L Hall
Oct 1, 1987·American Journal of Reproductive Immunology and Microbiology : AJRIM·G ScarselliS Pellegrini
Mar 1, 1985·American Journal of Reproductive Immunology and Microbiology : AJRIM·G G HaasL Blasco
Mar 1, 1985·American Journal of Reproductive Immunology and Microbiology : AJRIM·D J KayJ D Stanger
Jan 1, 1988·American Journal of Reproductive Immunology and Microbiology : AJRIM·B GocialJ Marmar
Jan 1, 1989·Archives of Andrology·F Nahhas, Z Blumenfield
Jul 1, 1987·The Journal of Urology·S L MandelbaumA H DeCherney
Jan 1, 1987·Archives of Andrology·Y C YanS S Koide
Jun 1, 1985·American Journal of Reproductive Immunology and Microbiology : AJRIM·G N ClarkeW I Johnston
Jul 15, 2003·Current Opinion in Obstetrics & Gynecology·Caleb B Kallen, Aydin Arici
Jun 1, 1988·American Journal of Reproductive Immunology and Microbiology : AJRIM·G N Clarke
Nov 1, 1987·American Journal of Reproductive Immunology and Microbiology : AJRIM·G G Haas
Oct 13, 1984·The Medical Journal of Australia·K L Harrison, J F Hennessey
Jan 9, 2003·The Urologic Clinics of North America·Peter J BurrowsLarry I Lipshultz

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