The internal burden of lead among children in a smelter town--a small area analysis

Environmental Research
M J TrepkaH E Wichmann

Abstract

Hettstedt, a city in former East Germany with a history of mining and smelting of nonferrous ores, has multiple lead waste deposits and the remains of a former lead and copper-silver smelter. A small-area analysis of lead concentrations in blood and in household dust was undertaken in a cross-sectional study to determine if children living near the sources had particularly high burdens of lead. The overall geometric mean of the region was 38.0 micrograms Pb/liter blood with a 95% confidence interval (CI) of 36.5-39.5. The burden of lead among children living in the region containing the lead tailings piles and adjacent smelters was almost twice as high (77.4 micrograms Pb/liter blood; 95% CI 65.0-92.0). It decreased in the areas farther northeast from the smelter. Lead levels in the children residing in areas southwest of the smelters were not appreciably elevated. The same pattern was found in house dust lead concentrations. This analysis helped target areas where follow-up is needed and found that not only distance from lead sources, but also meteorological factors played an important role in lead exposure.

References

Nov 1, 1978·Journal of Occupational Medicine. : Official Publication of the Industrial Medical Association·W N WatsonG C Giguere
Aug 1, 1977·Journal of the Air Pollution Control Association·A J YankelS D Walter
Jul 1, 1991·Archives of Environmental Contamination and Toxicology·T D MatteE L Baker
Feb 2, 1990·JAMA : the Journal of the American Medical Association·H L Needleman, C A Gatsonis
Apr 1, 1990·Regulatory Toxicology and Pharmacology : RTP·M J SteeleH S Strauss
Feb 1, 1990·Environmental Research·G DucoffreP Bruaux
Jan 1, 1988·International Archives of Occupational and Environmental Health·A BrockhausM Turfeld
Apr 1, 1986·Scandinavian Journal of Work, Environment & Health·C G ElinderI Overmark
Feb 1, 1974·American Journal of Diseases of Children·J W SayreI B Pless
Sep 1, 1983·Journal of the Air Pollution Control Association·B BrunekreefJ Boleij
Jun 1, 1981·Environmental Research·P J Landrigan, E L Baker
Jan 1, 1980·Archives of Environmental Health·S D WalterI H von Lindern
Sep 30, 1993·The Science of the Total Environment·A PönkäS Ahonen
Jan 1, 1994·International Archives of Occupational and Environmental Health·J BegerowL Dunemann
Jul 27, 1994·JAMA : the Journal of the American Medical Association·J L PirkleT D Matte

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Citations

Jan 21, 2000·Australian and New Zealand Journal of Public Health·M Warner-Smith, L Hancock
Apr 17, 2001·Occupational and Environmental Medicine·E KokkiJ Pekkanen
Jul 21, 2010·International Journal of Health Geographics·Robin L YoungThomas F Webster
Mar 25, 1999·Environmental Health Perspectives·A L BeninS Roda
Jan 5, 1999·Environmental Health Perspectives·J HeinrichH Wichmann
Feb 11, 2005·Journal of Occupational Health·Marek Jakubowski, Malgorzata Trzcinka-Ochocka
Aug 5, 2009·International Journal of Occupational and Environmental Health·Chamnong ThanapopPitchaya Phakthongsuk
Sep 9, 2010·Industrial Health·Orrapan UntimanonSutida Utapan
May 15, 2012·The Science of the Total Environment·Laiguo ChenXiaochun Peng
Jan 12, 2010·The Science of the Total Environment·Glauce Regina Costa de AlmeidaRaquel Fernanda Gerlach
Mar 26, 1998·The Science of the Total Environment·I MeyerU Lippold
Apr 5, 2003·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Torsten SchäferJoachim Heinrich
Aug 28, 2007·International Journal of Occupational and Environmental Health·Yvonne KohlhammerJoachim Heinrich
Aug 5, 2000·International Journal of Occupational and Environmental Health·S A CounterH Hu
Jul 23, 2003·International Journal of Hygiene and Environmental Health·Ines MeyerJoachim Heinrich
Feb 9, 2000·Environmental Research·B JacobH E Wichmann
Mar 23, 2002·Environmental Research·Monica Maria Bastos PaolielloBernardino Ribeiro Figueiredo
Jul 14, 2012·Journal of Occupational Health·Orrapan UntimanonPia K Verkasalo
Aug 6, 1999·Environmental Research·T SchäferH E Wichmann
Nov 15, 2003·Environmental Research·Yasmin von SchirndingReinette Blignaut
May 19, 2004·Environmental Research·Dorota JarosińskaWalter J Rogan
Jul 7, 2012·The Science of the Total Environment·Janae CsavinaA Eduardo Sáez
Jul 27, 2002·Australian and New Zealand Journal of Public Health·F BorelandS Reddan
Jul 11, 2013·Environmental Technology·Sandro MachadoGustavo Alonso Muñoz Magna
Aug 15, 2000·American Journal of Industrial Medicine·A LeroyerJ M Haguenoer

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