The International Nucleome Consortium

Nucleus
Satoshi Tashiro, Christian Lanctôt

Abstract

The eukaryotic genome adopts in the cell nucleus a 3-dimensional configuration that varies with cell types, developmental stages and environmental condition as well as between normal and pathological states. Understanding genome function will therefore require the elucidation of the structure-function relationship of the cell nucleus as a complex, dynamic biological system, referred to as the nucleome. This exciting and timely task calls for a multi-faceted, interdisciplinary and multi-national effort. We propose the establishment of an International Nucleome Consortium to coordinate this effort worldwide.

References

Jul 29, 2010·Molecular Systems Biology·Indika RajapakseMark Groudine
Jul 17, 2012·Trends in Genetics : TIG·Veronika Butin-IsraeliRobert D Goldman
Mar 7, 2013·Nature Structural & Molecular Biology·Giacomo Cavalli, Tom Misteli
Mar 12, 2013·Molecular Cell·Johan H Gibcus, Job Dekker
Jul 9, 2013·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Elphège P NoraEdith Heard
Jul 24, 2013·Annual Review of Genomics and Human Genetics·Wendy A Bickmore
Aug 10, 2013·Science·Vassilis RoukosTom Misteli
Nov 5, 2013·The EMBO Journal·Sevil SofuevaSuzana Hadjur
Jan 2, 2014·International Review of Cell and Molecular Biology·Angelo Rosa, Christophe Zimmer
Nov 5, 2014·Molecular Biology of the Cell·Thoru Pederson, John F Marko

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Citations

Oct 9, 2015·Critical Reviews in Biochemistry and Molecular Biology·Lijing YaoPeggy J Farnham
Apr 9, 2018·Biochemistry. Biokhimii︠a︡·T CremerC Cremer
Nov 7, 2017·Traffic·Shelley Sazer, Helmut Schiessel
Jan 30, 2020·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Thomas CremerChristoph Cremer

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Methods Mentioned

BETA
environmental stress
single-cell Hi-C
transgenics
super-resolution microscopy

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