The interplay between the disulfide bond formation pathway and cytochrome c maturation in Escherichia coli.

FEBS Letters
Despoina A I MavridouJulie M Stevens

Abstract

Heme attachment to c-type cytochromes in bacteria requires cysteine thiols in the CXXCH motif of the protein. The involvement of the periplasmic disulfide generation system in this process remains unclear. We undertake a systematic evaluation of the role of DsbA and DsbD in cytochrome c biogenesis in Escherichia coli and show unequivocally that DsbA is not essential for holocytochrome production under aerobic or anaerobic conditions. We also prove that DsbD is important but not essential for maturation of c-type cytochromes. We discuss the findings in the context of a model in which heme attachment to, and oxidation of, the apocytochrome are competing processes.

References

Jul 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·J A Peek, R K Taylor
Apr 1, 1980·Journal of Molecular Biology·M J Casadaban, S N Cohen
Jun 1, 1994·FEMS Microbiology Letters·C Iobbi-NivolJ A Cole
Dec 15, 1995·Cell·U GrauschopfJ C Bardwell
Apr 8, 1997·Biochemistry·P T ChiversR T Raines
Oct 29, 1998·Biochemical and Biophysical Research Communications·E ArslanL Thöny-Meyer
May 26, 2005·Protein Expression and Purification·F William Studier
Jul 12, 2005·Structure·Christian U StirnimannGuido Capitani
Jul 26, 2005·Bioscience, Biotechnology, and Biochemistry·Nobusuke KojimaYoshihiro Sambongi
Jun 21, 2006·Cellular and Molecular Life Sciences : CMLS·C U StirnimannG Capitani
Jul 12, 2007·The Journal of Biological Chemistry·Adele Di MatteoCarlo Travaglini-Allocatelli
Dec 18, 2007·Biochimica Et Biophysica Acta·Kenji Inaba, Koreaki Ito
Aug 9, 2008·FEBS Letters·Ian B RobertsonStuart J Ferguson
Nov 22, 2008·Biochemical Society Transactions·Despoina A I MavridouStuart J Ferguson
Sep 2, 2009·Microbiology and Molecular Biology Reviews : MMBR·Robert G KranzElaine R Frawley
May 15, 2010·The Journal of Biological Chemistry·Alan D GoddardStuart J Ferguson
Jan 19, 2011·Antioxidants & Redox Signaling·Stephen R ShouldiceJennifer L Martin
May 6, 2011·The Journal of Biological Chemistry·Despoina A I MavridouChristina Redfield
Oct 1, 2011·The FEBS Journal·Julie M StevensStuart J Ferguson

❮ Previous
Next ❯

Citations

Apr 26, 2013·The Journal of Biological Chemistry·Lauren DaveySong F Lee
Sep 21, 2013·Biochemistry·Despoina A I MavridouJulie M Stevens
Jan 24, 2013·IUBMB Life·Despoina A I MavridouJulie M Stevens
Jun 25, 2015·Frontiers in Microbiology·Katarzyna M Bocian-OstrzyckaElżbieta K Jagusztyn-Krynicka
Mar 19, 2014·Biochimica Et Biophysica Acta·Andreia F Verissimo, Fevzi Daldal
Nov 5, 2014·Journal of Bacteriology·Nicole AcostaTracy L Raivio
Apr 20, 2017·Nature Reviews. Microbiology·Benjamin EzratyJean-François Collet
Sep 13, 2018·The Journal of Biological Chemistry·Shevket H ShevketDespoina A I Mavridou
Oct 6, 2019·Applied and Environmental Microbiology·Kailun GuoHaichun Gao

❮ Previous
Next ❯

Software Mentioned

GeneSnap ( SYNGENE )

Related Concepts

Related Feeds

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.