PMID: 7992326Sep 1, 1994Paper

The interpretation of intensity and aggregation data for infections of Schistosoma haematobium

Transactions of the Royal Society of Tropical Medicine and Hygiene
M E WoolhouseD J Bradley


The relationships between mean intensities of infection, the aggregation of infection among hosts, and host age are analysed using data from 2 large (> 3000 individuals) field studies of Schistosoma haematobium infection. The data show a convex relationship between mean intensity and age, a convex relationship between an inverse index of aggregation and age, and an age-dependent relationship between the mean and aggregation of infection intensity when levels of infection are high. These patterns are qualitatively compared with the output of mathematical models based on an immigration-death process (model I), and incorporating age-dependent changes in the distribution of exposure to infection as suggested by field data (model II), or reductions in the rate of infection as a function of either current (model III) or cumulative (model IV) parasite burdens, that is, density-dependent processes without or with memory, respectively. Models II and III were able to reproduce observed patterns, but model IV, which is a possible representation of acquired immunity, was not. These results are consistent with the following assumptions: (i) age-related patterns of aggregation can be generated without recourse to density-dependent processes;...Continue Reading


Jun 27, 1991·Nature·M E WoolhouseS K Chandiwana
Jan 1, 1987·Transactions of the Royal Society of Tropical Medicine and Hygiene·H A WilkinsS Tulloch
Jan 1, 1973·Transactions of the Royal Society of Tropical Medicine and Hygiene·D J Bradley, F S McCullough
Feb 1, 1983·Experimental Parasitology·D A Dean
Jan 1, 1984·Transactions of the Royal Society of Tropical Medicine and Hygiene·H A WilkinsP J Moore
Jan 1, 1984·Transactions of the Royal Society of Tropical Medicine and Hygiene·H A WilkinsP J Moore
Aug 1, 1993·Acta Tropica·R D Gregory, M E Woolhouse
Jan 1, 1990·Parasitology Today·R A Wilson

❮ Previous
Next ❯


Oct 1, 1995·Parasitology Today·M E Woolhouse
Aug 26, 1998·Mathematical Biosciences·M S Chan, V S Isham
Aug 1, 1996·Tropical Medicine & International Health : TM & IH·M E WoolhouseS K Chandiwana
Dec 17, 1998·Tropical Medicine & International Health : TM & IH·C NeedhamD A Bundy
Jun 12, 1999·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·M G Basáñez, M Boussinesq
Jun 6, 2020·Tropical Medicine & International Health : TM & IH·Tariro L Mduluza-JokonyaTakafira Mduluza

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.