Apr 22, 1977

The intraocular pressure response of glaucomatous eyes to topically applied bupranolol. A pilot study

Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Albrecht Von Graefe's Archive for Clinical and Experimental Ophthalmology
G K KrieglsteinW Leydhecker

Abstract

Bupranolol 0.5% oily solution applied topically lowered intraocular pressure of glaucomatous eyes significantly. The pressure decrease is related to pretreatment pressure levels. The maximum effect occurred within 4 hours and lasted for more than 24 hours. No objective or subjective irritation could be attributed to the ophthalmic preparation. There was no significant effect on outflow facility, on blood pressure or tear flow. However, bupranolol produces local anesthesia on the eye. The problem of tachyphylaxis is discussed in the treatment of glaucoma with bupranolol eye drops.

  • References5
  • Citations9

References

  • References5
  • Citations9

Citations

Mentioned in this Paper

Local Anesthesia [PE]
Tears Body Substance
Diastolic Blood Pressure
Tachyphylaxis
Administration, Topical
Intraocular Pressure Test
Propanolamines
Bupranolol
Ocular Hypotension
Blood Pressure

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