PMID: 9427120Jan 14, 1998Paper

The intrinsic electrophysiological characteristics of fly lobula plate tangential cells: II. Active membrane properties

Journal of Computational Neuroscience
J HaagA Borst

Abstract

The voltage-gated currents in the fly lobula plate tangential cells were examined using the switched electrode voltage clamp technique. In CH cells, two currents were identified (Figs. 1, 2): a slow calcium inward current and a delayed rectifying, noninactivating potassium outward current. HS and VS cells appear to possess similar currents to CH cells, but in addition, exhibit a fast-activating sodium inward current and a sodium-activated potassium outward current (Figs. 3, 4). While the delayed rectifying potassium current in all three cell classes is responsible for the observed outward rectification described previously (Borst and Haag, 1996), the sodium inward current produced the fast and irregular spikelike depolarizations found in HS and VS cells but not in CH cells: When the sodium current is blocked by either. TTX or intracellular QX314, no more action potentials can be elicited in HS cells under current-clamp conditions (Fig. 5). As is demonstrated in HS cells, space clamp conditions are sufficient to suppress synaptically induced action potentials (Fig. 6). The currents described above were incorporated with the appropriate characteristics into compartmental models of the cells (Fig. 7, 8). The anatomical and electri...Continue Reading

Citations

Aug 30, 2003·Proceedings of the National Academy of Sciences of the United States of America·Hermann CuntzAlexander Borst
Mar 24, 2009·Journal of Neurogenetics·Shamprasad Varija RaghuDierk F Reiff
Apr 17, 2015·Journal of Neurophysiology·Janez PrešernJohannes Schul
Mar 6, 2002·Journal of Neurophysiology·Sandra Single, Alexander Borst
Jun 11, 2004·Journal of Neurophysiology·Daniel G WüstenbergDouglas A Baxter
Jun 15, 2007·Theoretical Biology & Medical Modelling·Hermann CuntzIdan Segev
Mar 17, 2010·Annual Review of Neuroscience·Alexander BorstDierk F Reiff
Feb 16, 2010·Nature Neuroscience·Gaby MaimonMichael H Dickinson
Oct 20, 2010·PLoS Computational Biology·Benjamin Torben-Nielsen, Klaus M Stiefel
May 17, 2011·PloS One·Shamprasad Varija Raghu, Alexander Borst
Jan 12, 2001·Journal of Neurophysiology·T G OertnerA Borst
Feb 13, 2001·Journal of Neurophysiology·H G KrappM Egelhaaf
Dec 30, 2008·PLoS Computational Biology·Hermann CuntzAlexander Borst
Nov 9, 2011·PloS One·Hubert Eichner, Alexander Borst
May 11, 2004·Nature Neuroscience·Juergen Haag, Alexander Borst
Aug 14, 2009·The European Journal of Neuroscience·Rafael KurtzMartin Egelhaaf
Aug 9, 2011·The European Journal of Neuroscience·Diana RienRafael Kurtz

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