The investigation on phytochemicals from Ferulago angulata (Schlecht) Boiss, indigenous to central parts of Iran

Natural Product Research
Seyed Mehdi RazaviShahabeddin Mirinejad

Abstract

Ferulago angulata (Schlecht) Boiss (Apiaceae) is a perennial herb distributed in the central parts of Iran. In this work, the essential oil of Ferulago angulata aerial parts collected from the central parts of Iran was obtained by using hydrodistillation analysed by GC and GC-MS. Air-dried and powdered plant roots were extracted with n-hexane, dichloromethane and methanol, respectively, using a Soxhlet apparatus. The n-hexane extract was subjected to preparative thin-layer chromatography using chloroform-acetone (95:5) as solvent system to yield two linear furanocoumarins, prantschimgin and oxypeucedanin. The structure of theisolated compounds was elucidated by using spectroscopic data such as (1)H NMR, (13)C NMR, UV and IR. The results of GC-MS analyses showed that γ-terpinolene (11.97%), α-pinene (10.00%), sabinene (6.89%), linalool (5.56%) and cis-ocimene (4.41%) were the main components among 51 constituents characterised in the oil. The oil exhibits considerable phytotoxic activity.

References

May 23, 2000·Phytochemistry·B JiménezM Grande
Mar 4, 2009·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Adriana BasileSergio Rosselli
Jul 17, 2009·Natural Product Research·Seyed Mehdi Razavi, Samad Nejad-Ebrahimi

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Citations

Feb 6, 2017·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Donata RicciDaniele Fraternale
Sep 29, 2017·Natural Product Research·Saeed TavakoliNarguess Yassa
Jul 24, 2020·Pharmacological Reports : PR·Ewelina KoziołBarbara Budzyńska
Mar 24, 2021·Journal of Ethnopharmacology·Natale BadalamentiMaurizio Bruno
Apr 2, 2021·The Journal of Pharmacy and Pharmacology·Wan Mohd Nuzul Hakimi Wan SallehAlene Tawang
Aug 29, 2021·Plants·Javad Mottaghipisheh

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