The involvement of Lyt-2 antigens in the lysis of virus-infected target cells by antigen specific anti-vesicular stomatitis virus cytotoxic T-lymphocytes

Immunology Letters
A H Hale

Abstract

The involvement of cell surface components associated with anti-viral cytotoxic T-lymphocytes (CTLs) in the specific lysis of virus-infected target cells was analyzed by the ability of different monoclonal antibodies to specifically inhibit CTL lytic activity. Utilizing monoclonal anti-Lyt antibodies, we showed that Lyt-2 antigens are closely associated with the CTL lytic event. The nature and limitations of this association are discussed.

References

Apr 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·E NakayamaL J Old
Feb 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·A H HaleH N Eisen

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Citations

Jan 3, 2013·Immunological Reviews·Jianming XieMark M Davis

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