The isocentric fast neutron therapy facility at Edinburgh

The British Journal of Radiology
D E BonnettC J Parnell


A second fast neutron beam for radiotherapy has been brought into operation at the Western General Hospital, Edinburgh. This beam is isocentrically mounted and can be rotated through +/- 120 deg from the vertical. Neutrons are produced by bombarding a thick beryllium target with 15 MeV deuterons. The provision of an isocentric facility enables some of the problems associated with poor beam penetration to be alleviated. The physical features of the isocentric facility are described with particular reference to the shielding and the methods employed to overcome problems of neutron activation. Both the prompt radiation leakage and the induced activity have been measured. It has been found that for the first eight months of operation the whole body dose-equivalent to radiographers was approximately 6 microSv (0.6 mrem) per patient treated. Dosimetry associated with the facility is discussed and an example of a seven field treatment plan for a bladder is presented.


Mar 1, 1979·The British Journal of Radiology·J R WilliamsC J Parnell
May 1, 1978·The British Journal of Radiology·D K Bewley, B C Page


Apr 1, 1992·The British Journal of Radiology·J Finch, D E Bonnett
Sep 1, 1983·The British Journal of Radiology·D E Bonnett
Jan 1, 1988·The British Journal of Radiology·D E BonnettD K Bewley
Feb 1, 1987·International Journal of Radiation Oncology, Biology, Physics·W DuncanJ R Williams
Mar 1, 1987·American Heart Journal·J A LopezR J Siegel
Aug 1, 1983·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·A BrahmeP Wootton
Mar 29, 2008·Physics in Medicine and Biology·Phillip J TaddeiWayne D Newhauser
Apr 1, 1984·Physics in Medicine and Biology·D K BewleyB C Page

Related Concepts

Malignant Neoplasm of Urinary Bladder
Dose-Response Relationship, Radiation
Fast Neutrons
Gray Units
Radiation Protection
Radiotherapy Dosage
Radiotherapy, Megavolt

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Pediculosis pubis

Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.

Rh Isoimmunization

Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.

Enzyme Evolution

This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Pharmacology of Proteinopathies

This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.