The isolated lung strip and single open tracheal ring: a convenient combination for characterizing Schultz Dale anaphylactic contractions in the peripheral and central airways of the guinea-pig

Clinical and Experimental Pharmacology & Physiology
K M LulichJ W Paterson

Abstract

1. The use of the isolated lung strip and single open tracheal ring for studying Schultz Dale anaphylactic contractions in both the peripheral and central airways is described. 2. This method is particularly relevant to studies of anaphylaxis because many preparations may be obtained from a single sensitized animal. 3. Isolated preparations from control guinea-pigs did not respond to ovalbumin, whereas the lung strip and trachea taken from guinea-pigs sensitized to ovalbumin, contracted markedly to that antigen. 4. The peripheral and central airways from sensitized animals responded in the same way to antigen challenge.

References

Jan 1, 1977·International Archives of Allergy and Applied Immunology·F Alonso-deFlorida, A Del Castillo
May 1, 1974·The Journal of Allergy and Clinical Immunology·P D JoinerF Hahn
Jan 1, 1968·The Journal of Pharmacy and Pharmacology·H Timmerman, N G Scheffer
Sep 1, 1952·The Journal of Pharmacy and Pharmacology·A AKCASU
Mar 1, 1960·The Journal of Pharmacy and Pharmacology·R W FOSTER
Jun 1, 1965·The Journal of Pharmacy and Pharmacology·J W CONSTANTINE

Citations

Jul 1, 1982·Biulleten' eksperimental'noĭ biologii i meditsiny·A V Barysheva
Apr 13, 1984·European Journal of Pharmacology·M H Saad, J F Burka
Apr 23, 1985·European Journal of Pharmacology·W KreutnerS Tozzi
Jan 1, 1987·International Journal of Immunopharmacology·L J RobichaudR L Adolphson
Jul 1, 1990·Journal of Ethnopharmacology·M E Addy, J F Burka

Related Concepts

Acetilcolina Cusi
Airway Resistance
Anaphylaxis
Metazoa
Cavia porcellus
Ceplene
Lung
Inotropism
Smooth Muscle
Ovalbumin

Related Feeds

Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.

Related Papers

The Journal of Pharmacy and Pharmacology
J W CONSTANTINE
Clinical and Experimental Pharmacology & Physiology
B R Creese, M A Denborough
The New England Journal of Medicine
M GriffinJ M Drazen
© 2021 Meta ULC. All rights reserved