PMID: 6975862May 1, 1981Paper

The isolated perfused frog eye: a useful preparation for the investigation of drug effects on retinal function

Journal of Pharmacological Methods
A H Friedman, A L Marchese

Abstract

The isolated frog eye perfused through its ophthalmic artery with a modified oxygenated Sickel's media responds to light stimuli of different wavelengths in a manner similar to that observed in the frog eye in vivo for periods of 9 hr and longer. Short- and long-duration field potentials from the globe (ERG) and optic nerve (ONP) can be recorded simultaneously. Drugs perfused through the eye can be shown to modify components of the ERG and ONP and to alter the flow rate of the perfusion media through the eye.

References

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Citations

Nov 15, 2006·Pharmaceutical Research·Martin J KoeberleClive G Wilson
Mar 17, 2009·The British Journal of Ophthalmology·D EllenbergD T Azar
Nov 29, 2011·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Jenifer MainsAndrew Urquhart
Apr 1, 1986·Current Eye Research·V A AlderM J Brown

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