PMID: 374995Jan 11, 1979Paper

The isolation and genetic characteristics of lambda transducing phages of the uvrA+ and uvrC+ genes of E. coli K12

Molecular & General Genetics : MGG
J I Auerbach, P Howard-Flanders

Abstract

Lambda transducing phages carrying the excision repair genes uvrA+ and uvrC+ were selected from a pool of lambda phages carrying EcoR1 fragments of E. coli DNA. These phages and also lambdauvrB+ (obtained from Gottesman) were used to make lysogens of excision-defective strains carrying uvrA-, uvrB- or uvrC-. Lambda uvrA+ was found to transduce strains carrying uvrA- but not those carrying uvrB- or uvrC-, to normal ultraviolet resistance. Similarly, lambdauvrB+ and lambdauvrC+ were found to complement only the corresponding uvr- allele. The lambda transducing phages were co-transduced with gal+ by P1 phage into lysogenic gal- recipients, and presumably were integrated at the normal prophage site.

References

Sep 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·M SpringerH Hennecke
Jan 1, 1975·Annual Review of Biochemistry·L GrossmanI Mahler
May 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·A Braun, L Grossman
May 1, 1969·Proceedings of the National Academy of Sciences of the United States of America·J C KaplanL Grossman

❮ Previous
Next ❯

Citations

Aug 1, 1982·Biochimie·W D RuppG B Sancar
Oct 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·S SharmaR E Moses
Jul 25, 1980·Nucleic Acids Research·J W ChaseW D Rupp
Sep 1, 1988·International Journal of Radiation Biology·J S Rubin
May 5, 1981·Journal of Molecular Biology·A SancarW D Rupp

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacteriophage: Phage Therapy

Phage therapy uses bacterial viruses (bacteriophages) to treat bacterial infections and is widely being recognized as an alternative to antibiotics. Here is the latest research.