The issue of mortality in schizophrenia

Thérapie
Emmanuelle Corruble

Abstract

First and second generation antipsychotic drugs have led to major therapeutic advances in the field of schizophrenia. Since the 50ties, they have enable schizophrenic patients to be treated as out-patients, contributing to the birth of a modern psychiatry. However, several therapeutic targets have not yet been reached. This paper will focus on mortality of schizophrenic patients, mortality due to suicide or mortality due to somatic conditions. In the future, therapeutic research in the field of psychotropic drugs should focus not only on improving efficacy on psychic targets and a better profile of tolerance, but also on improvement of mortality of schizophrenic patients treated with antipsychotics, which should decrease.

References

Mar 31, 1998·The British Journal of Psychiatry : the Journal of Mental Science·S Brown
Dec 26, 2001·Archives of General Psychiatry·W A RayK T Murray
Jul 12, 2002·Drugs·Peter M Haddad, Ian M Anderson
Jan 7, 2003·Archives of General Psychiatry·Herbert Y MeltzerUNKNOWN International Suicide Prevention Trial Study Group
Feb 4, 2003·The American Journal of Psychiatry·Martina C M RyanJogin H Thakore
Apr 2, 2004·The British Journal of Psychiatry. Supplement·Jogin H Thakore

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