PMID: 641380May 1, 1978Paper

The keratin polypeptides of psoriatic epidermis

The Journal of Investigative Dermatology
H P BadenJ Kubilus

Abstract

The polyacrylamide SDS electrophoretic pattern of protein extracted from the stratum corneum obtained by scraping the surface of involved skin of patients with psoriasis was different from that of uninvolved skin and normal controls. The pattern from superficial scales was similar to that of whole stratum corneum in the case of involved psoriatic epidermis but different in uninvolved and normal epidermis. These data indicate that the changes which are observed in the structural proteins during normal keratinization are not seen in involved psoriatic epidermis. In addition, the relative proportion of keratin polypeptides was different in involved psoriatic epidermis compared to normal skin. That these changes are not specific for psoriasis was shown by finding similar electrophoretic patterns with stratum corneum proteins from patients with other keratinizing disorders.

References

Aug 1, 1978·The Journal of Investigative Dermatology·H P Baden, L D Lee
Oct 1, 1976·The Journal of Investigative Dermatology·L D LeeB F Fleming
Nov 1, 1976·The Journal of Investigative Dermatology·H P BadenJ Kubilus
Nov 25, 1976·Nature·L D Lee, H P Baden
Dec 15, 1976·Journal of Molecular Biology·P M SteinertS B Zimmerman
Jul 1, 1975·The Biochemical Journal·P M Steinert
Oct 1, 1965·The Journal of Investigative Dermatology·G D Weinstein, E J Van Scott
Dec 1, 1966·The Journal of Investigative Dermatology·P FrostE J Van Scott
Aug 30, 1973·Biochimica Et Biophysica Acta·H P BadenB Fleming

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Citations

Mar 1, 1991·The Journal of Dermatology·S WatanabeH Takahashi
Oct 1, 1984·International Journal of Dermatology·H Ogawa, T Yoshiike
Sep 1, 1983·The British Journal of Dermatology·R KumarL A Chiero
Dec 1, 1983·Journal of Oral Pathology·I C Mackenzie, W H Binnie
Jan 1, 1982·Archives of Dermatological Research·J ViacJ Thivolet
Apr 1, 1992·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·S S QutaishatS Jablonska
Jan 1, 1985·Annals of the New York Academy of Sciences·T T SunR Eichner
Mar 1, 1990·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·E DabelsteenU Mandel
Nov 1, 1987·Cell and Tissue Kinetics·M HeenenP H Heenen
May 30, 1998·In Vitro Cellular & Developmental Biology. Animal·D OdaS P Lee
Jan 1, 1980·Archives of Dermatological Research·J ViacC Goujon
Jul 9, 2004·Journal of Cutaneous Pathology·Jag BhawanUNKNOWN IL-11 Psoriasis Study Group
Aug 1, 1988·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·H JahnF Brandrup
Apr 1, 1983·The Journal of Dermatology·N KatoY Miura
Jan 1, 1984·Archives of Dermatological Research·F KanekoY Miura
Jun 1, 1985·The British Journal of Dermatology·B A BernardM Darmon
Jun 1, 1982·The British Journal of Dermatology·Y KitajimaY Nozawa
Jul 1, 1984·The British Journal of Dermatology·J McGuireL Lightfoot
Jan 1, 1986·Archives of Dermatological Research·Y Katagata, K Aso
Jan 1, 1991·Archives of Dermatological Research·M ThewesD Mischke
Dec 1, 1987·International Journal of Dermatology·L M DiCiccoJ N Mansbridge
Apr 1, 1993·Journal of Cutaneous Pathology·S GonzálezI Pérez de Vargas
Jan 1, 1979·Pharmacology & Therapeutics·H P Baden
Feb 28, 1983·Biochimica Et Biophysica Acta·P E BowdenW J Cunliffe
Aug 1, 1980·The Journal of Investigative Dermatology·M ThalerK A Fisher
Sep 1, 1980·The Journal of Investigative Dermatology·M E GilmartinI M Freedberg
Mar 1, 1983·The Journal of Investigative Dermatology·A G MatoltsyP J Cliffel
Jul 1, 1983·The Journal of Investigative Dermatology·T T SunJ Woodcock-Mitchell
Feb 1, 1987·The Journal of Investigative Dermatology·F HornJ J Voorhees

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