The Kidney Transplant Morbidity Index (KTMI): a simple prognostic tool to help determine outcome risk in kidney transplant candidates

Progress in Transplantation : Official Publication, North American Transplant Coordinators Organization ... [et Al.]
Daniel PielochDavid A Laskow

Abstract

The Kidney Transplant Morbidity Index (KTMI) is a novel prognostic morbidity index to help determine the impact that pretransplant comorbid conditions have on transplant outcome. To use national data to validate the KTMI. Retrospective analysis of the Organ Procurement and Transplant Network/United Network for Organ Sharing database. The study sample consisted of 100 261 adult patients who received a kidney transplant between 2000 and 2008. Kaplan-Meier survival curves were used to demonstrate 3-year graft and patient survival for each KTMI score. Cox proportional hazards regression models were created to determine hazards for 3-year graft failure and patient mortality for each KTMI score. A sequential decrease in graft survival (0 = 91.2%, 1 = 88.2%, 2 = 85.4%, 3 = 81.7%, 4 = 77.8%, 5 = 74.0%, 6 = 69.8%, and ≥ 7 = 68.7) and patient survival (0 = 98.2%, 1 = 96.6%, 2 = 93.7%, 3 = 89.7%, 4 = 84.8%, 5 = 80.8%, 6 = 76.0%, and ≥ 7 = 74.7%) is seen as KTMI scores increase. The differences in graft and patient survival between KTMI scores are all significant (P< .001) except between 6 and ≥ 7. Multivariate regression analysis reveals that KTMI is an independent predictor of higher graft failure and patient mortality rates and that ris...Continue Reading

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Citations

Aug 11, 2017·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Giovanni VarottiIris Fontana
May 9, 2019·Seminars in Cardiothoracic and Vascular Anesthesia·Natalie K SmithTetsuro Sakai
Dec 2, 2020·American Journal of Surgery·Giovanni VarottiIris Fontana

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