PMID: 558054Mar 1, 1977Paper

The kinetics of contact inhibition in mammalian cells

Cell and Tissue Kinetics
P SchmialekB Zapf

Abstract

To elucidate the process of contact inhibition in mammalian cells, we investigated the kinetics of growth arrest in [3H]thymidine labelled embryonic chinese hamster (Cricetulus griseus L.) cells after the addition of various concentrations of unlabelled cells. It was observed that after the contact inhibition concentration had been reached, the cells grew undisturbed for one more generation. In the following 24 hr the concentration fell back to the level at the beginning of the experiment and stayed there.

References

Dec 1, 1978·Journal of Microscopy·P SchmialekM Nündel
Nov 1, 1976·Biotechnology and Bioengineering·P SchmialekB Zapf
Jan 1, 1971·Proceedings of the National Academy of Sciences of the United States of America·C Ceccarini, H Eagle
Sep 1, 1972·Journal of Theoretical Biology·C R Stewart
Feb 1, 1973·Journal of Cellular Physiology·E Martz, M S Steinberg
Feb 1, 1968·Journal of Cellular Physiology·L Schutz, P T Mora
Feb 11, 1966·Science·G F Whitmore, S Gulyas
Oct 1, 1956·The Journal of Experimental Medicine·S J CIECIURAT T PUCK
Oct 1, 1957·Experimental Cell Research·M ABERCROMBIEH M KARTHAUSER
May 23, 1958·Science·R B PAINTERW L HUGHES
Oct 1, 1958·Experimental Cell Research·M ABERCROMBIE, E J AMBROSE
Dec 1, 1961·Experimental Cell Research·L HAYFLICK, P S MOORHEAD
Feb 1, 1965·Proceedings of the National Academy of Sciences of the United States of America·R G HAM
Jun 1, 1965·The Journal of Surgical Research·G E MOORE, K ULRICH
Jun 9, 1962·Nature·J NAGINGTON, R I GREAVES

❮ Previous
Next ❯

Citations

Jan 19, 2018·International Journal of Molecular Sciences·Jessica Hoarau-VéchotJennifer Pasquier

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.