PMID: 16538104Mar 16, 2006Paper

The kinetics of hepatitis C virus

European Journal of Gastroenterology & Hepatology
Eva Herrmann, Stefan Zeuzem

Abstract

The kinetics of hepatitis C virus (HCV) RNA during the first weeks of interferon-based antiviral therapy can be analysed by specific mathematical models. Those models have been inspired by previous work on the kinetics of human immune deficiency virus (HIV) and hepatitis B virus (HBV) during antiviral therapy and are able to summarize important features of early response to antiviral therapy in patients chronically infected with HCV. Kinetic parameters of the underlying biological processes as viral clearance and infected cell loss as well as an efficiency factor of therapy on viral production can be obtained when fitting frequent quantifications of HCV RNA with such models. The main aims of analysing hepatitis C viral kinetics include the efficient comparison of different treatment regimens, prediction of virological response, and conclusions on antiviral mechanisms of therapy.

References

Oct 1, 1995·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M Martinot-PeignouxV Milotova
Jul 1, 1997·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·N P LamT J Layden
Jul 10, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·S ZeuzemW K Roth
Dec 29, 1999·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·T PoynardJ Albrecht
Jul 7, 2000·The Journal of Infectious Diseases·A U NeumannT J Layden
Dec 7, 2000·The New England Journal of Medicine·S ZeuzemM J Brunda
Jul 7, 2001·The New England Journal of Medicine·G M Lauer, B D Walker
Aug 2, 2001·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K L LindsayUNKNOWN Hepatitis Interventional Therapy Group
Aug 9, 2001·Proceedings of the National Academy of Sciences of the United States of America·R T ChungE V Schmidt
Mar 27, 2002·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Maria ButiRafael Esteban
Aug 13, 2002·European Journal of Gastroenterology & Hepatology·Roel E SentjensHenk W Reesink
Sep 27, 2002·The New England Journal of Medicine·Michael W FriedJian Yu
Oct 31, 2002·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Leonard B Seeff
Oct 31, 2002·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Hashem B El-Serag
Oct 31, 2002·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Teresa L Wright
Feb 1, 2003·Journal of Viral Hepatitis·S J CotlerD M Jensen
Feb 26, 2003·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Thomas BergStefan Zeuzem
Apr 30, 2003·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Haizhen ZhuChen Liu
May 30, 2003·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jennifer E Layden-AlmerThomas J Layden
Aug 29, 2003·Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie·Louis W C LiuJenny Heathcote
Sep 13, 2003·Journal of Viral Hepatitis·P HalfonP Cacoub
Nov 19, 2003·The Journal of Infectious Diseases·Francesca J TorrianiAlan S Perelson
Jan 15, 2004·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Andrew H TalalAlan S Perelson
Feb 28, 2004·Gastroenterology·Jean-Michel PawlotskyDaniel Dhumeaux
Mar 5, 2004·Annals of Internal Medicine·Stephanos J HadziyannisUNKNOWN PEGASYS International Study Group
Nov 27, 2004·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Bernd KronenbergerStefan Zeuzem

❮ Previous
Next ❯

Citations

Mar 21, 2007·Antimicrobial Agents and Chemotherapy·Liangjun LuAkhteruzzaman Molla
Aug 28, 2007·International Journal of Nanomedicine·Heinz Zoller, Wolfgang Vogel
Nov 16, 2006·Expert Opinion on Therapeutic Targets·Daniel YerlyAndreas Cerny
Dec 24, 2015·Viruses·Asma Ahmed, Daniel J Felmlee
Oct 5, 2010·Journal of Theoretical Biology·Alison K McLeanMark M Tanaka
Nov 27, 2007·Liver International : Official Journal of the International Association for the Study of the Liver·Nyingi Kemmer, Guy W Neff
Jan 14, 2012·Memórias do Instituto Oswaldo Cruz·Magda Cristina Bernardino CastilhoOrlando da Costa Ferreira Júnior
Nov 3, 2015·World Journal of Hepatology·James Fung

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Related Papers

Hepatology : Official Journal of the American Association for the Study of Liver Diseases
Jennifer E Layden-AlmerThomas J Layden
© 2021 Meta ULC. All rights reserved