PMID: 9542511Apr 18, 1998Paper

The lack of age as a significant prognostic factor in non-metastatic breast cancer

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
A EzzatS Bazarbashi

Abstract

To determine the prognostic significance of age at diagnosis in women with non-metastatic breast cancer. A retrospective review of all newly diagnosed breast cancer in women between 1975 and 1991 was carried out at a tertiary Oncology Referral Centre. Patients were divided into three age groups: < 40 years, 40-50 years and > 50 years. Demographic and management/outcome details were collected from patients with UICC stages I-III. The effect of age on overall and relapse free survival was analysed by standard statistical methods. Of 1289 new cases registered during the study period, 710 (55%) were UICC stages I-III. Of the latter group 250 (35%) women were in the age group of less than 40 years, 237 (33%) were between 40 and 50 years and 223 (32%) were older than 50 years. Women from the younger age group had a higher proportion of breast-conserving surgery, and adjuvant chemo- and radiation therapy, while the proportion of hormone therapy usage was higher in older women. There was no difference in overall survival (P = 0.64) and relapse-free survival (P = 0.53) between the three age groups. In this study, age was not a prognostic factor in predicting overall or relapse-free survival in women with breast cancer.

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Citations

Apr 23, 2002·Journal of Surgical Oncology·Byeong-Woo ParkKyong Sik Lee
Dec 23, 2003·Pathology Oncology Research : POR·Mansour Al-MoundhriC Grant
Aug 1, 2007·The Indian Journal of Surgery·Vikash KumarH S Shukla
Mar 17, 2004·The Breast : Official Journal of the European Society of Mastology·M Al-MoundhriC Grant
Mar 27, 2001·European Journal of Obstetrics, Gynecology, and Reproductive Biology·G VorgiasE Tzoracoeleftherakis
Apr 18, 2002·International Journal of Radiation Oncology, Biology, Physics·Jason Chia-Hsien ChengAndrew T Huang
Dec 8, 2000·Breast Cancer Research and Treatment·S H ChengA T Huang
Jun 24, 2005·ANZ Journal of Surgery·Chek Siang FooSu Ming Tan
May 20, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Hans WildiersPatrick Neven
Dec 30, 2003·International Journal of Cancer. Journal International Du Cancer·Kee Seng ChiaHin Peng Lee
Jul 7, 2015·Cellular & Molecular Biology Letters·Vincent DigiacomoDaniel Meruelo

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