PMID: 2485485Jan 1, 1989Paper

The lack of clinical value of laboratory parameters in predicting outcome in acute renal failure

Renal Failure
Z DurakovićS Durakovic

Abstract

In 55 patients with either the oliguric and nonoliguric form of acute renal failure, some laboratory parameters for the analysis of prerenal and intrinsic types of acute renal failure were examined. The parameters were analyzed within 7 days of the clinically known beginning of the illness. The parameters were analyzed as follows: sodium in urine, creatinine urine/plasma ratio, urine osmolality, osmolality urine/plasma ratio, renal failure index, and fractional excretion of filtered sodium. Hemodialysis was performed in 29 of the 55 patients. The oliguric form of acute renal failure was present in 49 of the 55 patients. In relation to renal failure index, prerenal acute renal failure was present in 7 patients and intrinsic acute renal failure in 48. It appears that in patients with a clinical diagnosis of prerenal acute renal failure, the urinary parameters do not separate them from those with acute tubular necrosis. It also appears that in patients with laboratory diagnosis of prerenal acute renal failure (i.e., a RFT less than 1.0), the response to treatment is unpredictable and in fact may have a worse prognosis than in those with a RFI greater than 1.0 (5/7 deaths vs 10/48 deaths).

References

Aug 1, 1979·Kidney International·W F Finn, R L Chevalier
Jul 1, 1978·Annals of Internal Medicine·T R MillerR W Schrier
May 19, 1977·The New England Journal of Medicine·R J AndersonR W Schrier
Aug 9, 1976·JAMA : the Journal of the American Medical Association·C H Espinel
Jan 9, 1975·The New England Journal of Medicine·J T Harrington, J J Cohen
Nov 1, 1975·Circulation Research·W J ArendshorstC W Gottschalk
Sep 1, 1986·The Medical Clinics of North America·H L Corwin, J V Bonventre
Jan 1, 1987·Renal Failure·A L LintonK Solez
Aug 1, 1986·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·J F WalkerA L Linton
Jan 1, 1985·Archives of Internal Medicine·S ZarichJ R Diamond
Mar 1, 1985·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·H TsukamotoC Largman
Jun 1, 1985·Kidney International·S M Moran, B D Myers
Sep 1, 1983·Pediatric Research·G W FernaldF W Henderson
Mar 1, 1983·Proceedings of the Society for Experimental Biology and Medicine·D GoldfarbH E Eliahou
Dec 1, 1981·The American Journal of Medicine·D E Oken
Aug 1, 1980·Intensive Care Medicine·A Martinez-VeaJ Millá

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Citations

May 23, 1998·The Veterinary Clinics of North America. Small Animal Practice·G F Grauer
Jul 1, 1994·Irish Journal of Medical Science·C G Flynn

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