The late news on baff in autoimmune diseases

Autoimmunity Reviews
Pierre Youinou, Jacques-Olivier Pers

Abstract

The B cell-activating factor of the tumor-necrosis factor family (BAFF) plays a dominant role in the B cell homeostasis. By rescuing autoreactive B cells, excessive BAFF favors the development of autoimmune diseases. Given the numbers of variants of this B cell-specific cytokine, caution must be exercized when determining its serum level. Alternate splice isoforms, such as Δ3 BAFF and Δ4 BAFF, have been identified. They raise the possibility that their overproduction impact the synthesis of full-length BAFF.

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Citations

Jul 13, 2011·Arthritis Research & Therapy·Pierre Youinou, Jacques-Olivier Pers
Jan 15, 2014·Cytokine & Growth Factor Reviews·Maogen ChenSong Guo Zheng
Aug 4, 2012·La Presse médicale·Pierre Youinou, Jacques-Olivier Pers
Jul 31, 2012·La Presse médicale·Nishath HamzaCees G M Kallenberg
Aug 7, 2012·Journal of Autoimmunity·Christophe JaminJacques-Olivier Pers
Jul 4, 2012·Journal of Autoimmunity·Ayan LahiriJacques-Olivier Pers
Mar 6, 2012·Autoimmunity Reviews·Jacques-Olivier Pers
Jan 13, 2011·Autoimmunity Reviews·Margherita ZenAndrea Doria
Jan 13, 2011·Autoimmunity Reviews·Marisa Neves, José Delgado Alves
May 20, 2015·Hämostaseologie·Tamam Bakchoul, Ulrich J Sachs
May 8, 2013·The British Journal of Dermatology·N WutteE Aberer
Aug 14, 2012·Proteomics·Miroslava Stastna, Jennifer E Van Eyk
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May 17, 2013·Seminars in Hematology·Dana YehudaiZahava Vadasz
Jul 20, 2016·Rheumatic Diseases Clinics of North America·Joana CamposFrancesca Barone
Jun 4, 2019·Journal of Clinical Medicine·Luz Kelly AnzolaAlberto Signore
Aug 5, 2017·Experimental Dermatology·Minna E KubinRiitta Palatsi
May 5, 2020·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Zong-Li RenXin Cai

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