The learning curve associated with the introduction of the subcutaneous implantable defibrillator

Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
Reinoud E KnopsIDE and EFFORTLESS investigators

Abstract

The subcutaneous implantable cardioverter defibrillator (S-ICD) was introduced to overcome complications related to transvenous leads. Adoption of the S-ICD requires implanters to learn a new implantation technique. The aim of this study was to assess the learning curve for S-ICD implanters with respect to implant-related complications, procedure time, and inappropriate shocks (IASs). In a pooled cohort from two clinical S-ICD databases, the IDE Trial and the EFFORTLESS Registry, complications, IASs at 180 days follow-up and implant procedure duration were assessed. Patients were grouped in quartiles based on experience of the implanter and Kaplan-Meier estimates of complication and IAS rates were calculated. A total of 882 patients implanted in 61 centres by 107 implanters with a median of 4 implants (IQR 1,8) were analysed. There were a total of 59 patients with complications and 48 patients with IAS. The complication rate decreased significantly from 9.8% in Quartile 1 (least experience) to 5.4% in Quartile 4 (most experience) (P = 0.02) and non-significantly for IAS from 7.9 to 4.8% (P = 0.10). Multivariable analysis demonstrated a hazard ratio of 0.78 (P = 0.045) for complications and 1.01 (P = 0.958) for IAS. Dual-zone pr...Continue Reading

References

Dec 7, 2007·Postgraduate Medical Journal·A N HopperW G Lewis
Apr 23, 2009·JAMA : the Journal of the American Medical Association·Jeptha P CurtisHarlan M Krumholz
Sep 3, 2009·The New England Journal of Medicine·Arthur J MossUNKNOWN MADIT-CRT Trial Investigators
May 14, 2010·The New England Journal of Medicine·Gust H BardyAndrew A Grace
Feb 18, 2011·Circulation. Arrhythmia and Electrophysiology·Andrew D KrahnUNKNOWN Ontario ICD Database Investigators
Oct 16, 2012·Journal of the American College of Cardiology·Louise R A Olde NordkampReinoud E Knops
May 28, 2013·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Reinoud E KnopsArthur A M Wilde
Dec 11, 2013·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Kirsten M KooimanJoris R de Groot
Mar 29, 2014·European Heart Journal·Pier D LambiaseUNKNOWN EFFORTLESS Investigators
Oct 23, 2014·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Fredrik GadlerCecilia Linde
Jan 13, 2015·Journal of Cardiovascular Electrophysiology·Amy J BrisbenMichael R Gold
Jun 1, 2015·International Journal of Cardiology·Louise R A Olde NordkampReinoud E Knops

❮ Previous
Next ❯

Citations

Jan 5, 2016·European Heart Journal·Jan SteffelGerhard Hindricks
Sep 2, 2016·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Serge BovedaNikolaos Dagres
Sep 20, 2016·Journal of Cardiothoracic and Vascular Anesthesia·Michael K EssandohEmile G Daoud
Oct 16, 2016·Herzschrittmachertherapie & Elektrophysiologie·Claudia Schaarschmidt, Christof Kolb
Nov 5, 2016·Journal of the American College of Cardiology·Tom F BrouwerReinoud E Knops
Nov 14, 2016·Revista Española De Cardiología·Reinoud E Knops, Tom F Brouwer
Dec 13, 2016·Pacing and Clinical Electrophysiology : PACE·Michael R GoldLucas Boersma
Feb 6, 2017·Clinical & Experimental Ophthalmology·Miriam C KeaneUNKNOWN Contributors to the Australian Corneal Graft Registry
Apr 7, 2017·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Ali A MithaniAndrea M Russo
Mar 2, 2018·Pacing and Clinical Electrophysiology : PACE·Andrea DroghettiMassimiliano Marini
Jul 15, 2017·World Journal of Cardiology·Paolo FerreroAlan Graham Stuart
Dec 23, 2016·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Joachim WinterStephen O'Connor
Dec 1, 2017·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Floor C W M SaldenKevin Vernooy
Jan 12, 2017·Circulation. Arrhythmia and Electrophysiology·Tom F BrouwerReinoud E Knops
Nov 1, 2018·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·A B E QuastR E Knops
Aug 10, 2019·Pacing and Clinical Electrophysiology : PACE·Beatriz León SalasPedro Serrano-Aguilar
Nov 30, 2019·Journal of Cardiovascular Electrophysiology·Matteo ZiacchiAndrea Droghetti
Feb 28, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Boris RudicJürgen Kuschyk
Apr 16, 2020·Diabetes & Vascular Disease Research : Official Journal of the International Society of Diabetes and Vascular Disease·Elif KayaReza Wakili
Apr 9, 2020·Pacing and Clinical Electrophysiology : PACE·Larry M BaddourBradley P Knight
May 4, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Andreas HaeberlinTobias Reichlin
Oct 6, 2019·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Kevin WillyGerrit Frommeyer
Nov 2, 2019·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Kevin WillyGerrit Frommeyer
Jul 29, 2020·Pacing and Clinical Electrophysiology : PACE·Willeke van der StuijtReinoud E Knops
Sep 15, 2020·Pacing and Clinical Electrophysiology : PACE·Prabhpreet SinghRaul Weiss
Jun 28, 2018·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Markus BettinGerrit Frommeyer
Sep 27, 2018·Herz·J SperzelA Hain
Mar 20, 2019·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Nils BögeholzLars Eckardt
Mar 25, 2019·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Kevin WillyGerrit Frommeyer
Sep 13, 2019·Journal of Cardiovascular Electrophysiology·Anne-Floor B E QuastReinoud E Knops
Mar 15, 2018·Journal of Clinical Medicine·Carmen AdduciPietro Francia
Jun 26, 2018·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Massimo Stefano SilvettiFabrizio Drago
Jul 16, 2019·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Kevin WillyGerrit Frommeyer
May 18, 2018·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Tom F BrouwerJeffrey S Healey
Aug 15, 2018·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Fleur V Y TjongUNKNOWN Observational Study Investigators
Dec 10, 2019·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Toshimasa OkabeMichael K Essandoh
Dec 10, 2020·Journal of Cardiovascular Electrophysiology·Danilo RicciardiGiovanni Battista Forleo
Nov 21, 2020·JACC. Clinical Electrophysiology·Martin C BurkeMichael R Gold
Nov 20, 2020·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Roberto RordorfAlessandro Vicentini
Nov 28, 2017·Cardiac Electrophysiology Clinics·Jonathan Weinstock, Christopher Madias
Nov 21, 2019·Journal of cardiology·Kevin WillyGerrit Frommeyer
May 26, 2018·JACC. Clinical Electrophysiology·David S FrankelAndrew E Epstein
May 12, 2021·Open Heart·Jorio MascheroniAnthony G Gallagher
Nov 2, 2020·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Kevin WillyGerrit Frommeyer

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Cardiovascular Electrophysiology
Douglas R MoorePugazhendhi Vijayaraman
Pacing and Clinical Electrophysiology : PACE
William J BonneyRobert H Pass
Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA
Zhen-yu LouXue-qi Li
© 2021 Meta ULC. All rights reserved