PMID: 9533383Apr 9, 1998Paper

The left hemisphere and the selection of learned actions

Neuropsychologia
M F RushworthR E Passingham

Abstract

The left hemisphere's dominance for movement is well known. The basis of its dominance is less clear. We have tested 16 left hemisphere (LH) patients, 17 right hemisphere (RH) patients and 12 neurologically normal controls on a battery of five tasks. The tasks were based on animal lesion and recording studies, and human imaging and magnetic stimulation studies that identified two distributed systems that are important for the selection of motor responses and object-oriented responses. The LH patients were impaired on three response selection tasks: learning to select between joystick movement responses instructed by visual cues; learning to select between analogous object-oriented responses instructed by visual cues; learning to select movements in a sequence. Although we replicated the finding that LH damage impairs sequencing, some of the impaired tasks had no sequencing element. We therefore argue that the LH deficits are best explained as an impairment of response selection. This was confirmed by showing that LH subjects were unimpaired on a more demanding task-object discrimination learning-which imposed a greater memory load but had no response selection element. Moreover, the LH deficits could not be attributed to disorg...Continue Reading

References

Feb 1, 1992·Brain : a Journal of Neurology·M P AlexanderC Palumbo
Jun 1, 1992·Brain : a Journal of Neurology·D L Harrington, K Y Haaland
Jan 1, 1991·Neuropsychologia·D L Harrington, K Y Haaland
Jun 1, 1991·Brain : a Journal of Neurology·E A GaffanJ R Hodges
Jan 1, 1991·Experimental Brain Research·M P DeiberR S Frackowiak
Feb 1, 1990·Brain : a Journal of Neurology·U Halsband, H J Freund
Feb 1, 1990·Brain : a Journal of Neurology·H PoiznerK M Heilman
Jan 1, 1989·Experimental Brain Research·A G CanavanR E Passingham
Feb 1, 1988·Brain : a Journal of Neurology·J L BarburJ M Findlay
Mar 1, 1989·The Journal of Comparative Neurology·B Seltzer, D N Pandya
Oct 1, 1988·Brain : a Journal of Neurology·E De Renzi, F Lucchelli
Dec 1, 1988·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·C Barbieri, E De Renzi
Jan 1, 1988·Experimental Brain Research·R E Passingham
Apr 1, 1986·Journal of Neurology, Neurosurgery, and Psychiatry·A Basso, S Della Sala
Jan 1, 1986·Neuropsychologia·K Poeck
Sep 1, 1986·Journal of Neurology, Neurosurgery, and Psychiatry·E De RenziG Crisi
Jan 1, 1985·Neuropsychologia·G W Jason
Dec 1, 1985·Behavioural Brain Research·U Halsband, R E Passingham
Jun 1, 1974·Brain : a Journal of Neurology·D Kimura, Y Archibald
Apr 1, 1981·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·G Lehmkuhl, K Poeck
Jun 1, 1982·Brain : a Journal of Neurology·E De RenziP Sorgato
Sep 1, 1984·Brain : a Journal of Neurology·A Kertesz, J M Ferro
Sep 1, 1983·Journal of Neurology, Neurosurgery, and Psychiatry·E AgostoniG Tredici
Sep 1, 1983·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·E De RenziA Vecchi
Jan 1, 1982·Neuropsychologia·A Kertesz, P Hooper
Aug 1, 1980·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·K Poeck, G Lehmkuhl
Feb 5, 1993·Science·J E Hoover, P L Strick
Mar 1, 1993·Journal of Neurology, Neurosurgery, and Psychiatry·C PapagnoA Basso
Jan 1, 1995·Experimental Brain Research·Y C ChenR E Passingham
Feb 1, 1995·Brain : a Journal of Neurology·H PoiznerK M Heilman
Oct 1, 1994·Brain : a Journal of Neurology·M A ClarkK M Heilman
Feb 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·M PetridesE Meyer
Feb 1, 1996·Brain : a Journal of Neurology·P P Pramstaller, C D Marsden
Mar 1, 1996·Cerebral Cortex·S T GraftonM A Arbib
Mar 1, 1996·Brain Research. Cognitive Brain Research·G GoldenbergJ Spatt
Oct 1, 1996·Brain : a Journal of Neurology·J HermsdörferG Goldenberg
Jan 7, 1998·Experimental Brain Research·M F RushworthR E Passingham

❮ Previous
Next ❯

Citations

Jul 29, 2009·Brain Structure & Function·Christiana M LeonardChristine Chiarello
Sep 19, 2008·Brain Topography·Leila S Overney, Olaf Blanke
Oct 30, 2008·Current Neurology and Neuroscience Reports·Rachel Goldmann Gross, Murray Grossman
Mar 17, 2004·Brain Research. Cognitive Brain Research·Bert SteenbergenDavid A Rosenbaum
Nov 5, 2003·NeuroImage·M F S RushworthJ T Devlin
Apr 28, 2004·NeuroImage·Christina S KonenRüdiger J Seitz
Apr 25, 2000·Neuropsychologia·A Sunderland, S M Sluman
Mar 18, 1999·Neuropsychologia·N D SchluterR E Passingham
Apr 2, 2003·Brain Research. Cognitive Brain Research·Katja WerheidD Yves von Cramon
Apr 27, 2001·Trends in Cognitive Sciences·J L. Bradshaw
Mar 4, 2005·Journal of Clinical and Experimental Neuropsychology·Lucie GodboutS Gagnon
May 10, 2007·Developmental Neuropsychology·Karen Chipman, Elizabeth Hampson
Nov 15, 2011·Brain : a Journal of Neurology·Pratik K MuthaKathleen Y Haaland
Nov 23, 2011·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Scott H Frey, Daniel J Povinelli
Mar 4, 2011·Journal of Neurophysiology·Mattia MarangonScott H Frey
Aug 10, 2004·Journal of Cognitive Neuroscience·Miwa MatsubaraShotai Kobayashi
Sep 22, 2001·Neuropsychologia·A C Nobre
Feb 13, 2001·Neuropsychologia·N D SchluterR E Passingham
Nov 19, 2011·Research in Developmental Disabilities·P M van KampenG J P Savelsbergh
Jan 27, 2010·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Gavin BuckinghamDavid P Carey
Dec 17, 2014·The European Journal of Neuroscience·Lara BardiDaniela Mapelli
Jun 20, 2006·Neuropsychologia·Karen Chipman, Elizabeth Hampson
Aug 8, 2015·Biological Psychology·Dimitrios Kourtis, Guy Vingerhoets
May 25, 2001·NeuroImage·R Leiguarda
Dec 10, 1999·Brain and Cognition·F H Previc
May 8, 2007·Neuron·Jacinta O'SheaMatthew F S Rushworth
Dec 1, 2012·NeuroImage·Robert M HardwickSimon B Eickhoff
Sep 25, 2010·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Michele RibolsiGiacomo Koch
Jul 11, 2014·Behavioural Brain Research·Verónica Mäki-MarttunenRamón C Leiguarda
Feb 14, 2012·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·J CespónF Díaz
Mar 30, 2013·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Christophe JarryDidier Le Gall
Dec 3, 2014·Research in Developmental Disabilities·Michèle MolinaFrançois Jouen
Dec 19, 2013·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·M Nisiyama, L E Ribeiro-do-Valle

❮ Previous
Next ❯

Related Concepts

Related Feeds

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.