The Leicester Cough Monitor: preliminary validation of an automated cough detection system in chronic cough

The European Respiratory Journal
S S BirringI D Pavord

Abstract

Chronic cough is a common condition that presents to both primary and secondary care. Assessment and management are hampered by the absence of well-validated outcome measures. The present study comprises the validation of the Leicester Cough Monitor (LCM), an automated sound-based ambulatory cough monitor. Cough frequency was measured with the LCM and compared with coughs and other sounds counted manually over 2 h of a 6-h recording by two observers in nine patients with chronic cough in order to determine the sensitivity and specificity of the LCM. Automated cough frequency was also compared with manual counts from one observer in 15 patients with chronic cough and eight healthy subjects. All subjects underwent 6-h recordings. A subgroup consisting of six control and five patients with stable chronic cough underwent repeat automated measurements > or = 3 months apart. A further 50 patients with chronic cough underwent 24-h automated cough monitoring. The LCM had a sensitivity and specificity of 91 and 99%, respectively, for detecting cough and a false-positive rate of 2.5 events x h(-1). Mean+/-SEM automated cough counts x patient x h(-1) was 48+/-9 in patients with chronic cough and 2+/-1 in the control group (mean difference...Continue Reading

Citations

Aug 22, 2009·Lung·Lorcan McGarvey
Oct 14, 2009·Lung·Kai K Lee, Surinder S Birring
Dec 15, 2010·American Journal of Respiratory and Critical Care Medicine·Surinder S Birring
Mar 9, 2013·American Journal of Respiratory and Critical Care Medicine·Kai K LeeSurinder S Birring
Mar 17, 2010·Biomedical Engineering Online·Malgorzata KrajnikEwa Jassem
Nov 20, 2008·Cough·Amisha SingapuriChristopher E Brightling
Dec 3, 2011·Cough·Sophie LeconteJean-Marie Degryse
Oct 30, 2015·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Yaniv ZigelJacob Urkin
Sep 10, 2015·Lung·Timothy Tully, Surinder S Birring
Aug 10, 2013·Chest·Kristine M SchmitGillian D Sanders
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Jul 17, 2012·Chest·Kai K LeeSurinder S Birring
Feb 8, 2011·Pulmonary Pharmacology & Therapeutics·L P A McGarvey
Jan 25, 2011·Pulmonary Pharmacology & Therapeutics·Surinder S Birring
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